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Choriocarcinoma is a malignant, trophoblastic [1] cancer, usually of the placenta. It is characterized by early hematogenous spread to the lungs. It is characterized by early hematogenous spread to the lungs.
The choriocarcinoma has 2 significant subtypes including gestational and non-gestational and they are differentiated by their different biological feature and prognosis. [4] Signs and symptoms of GTN will appear vary from person to person and depending upon the type of the disease.
Forms terms denoting conditions relating to eating or ingestion Greek φαγία (phagía) eating < φᾰγεῖν (phageîn), to eat Sarcophagia-phago-eating, devouring Greek -φᾰ́γος (-phágos), eater of, eating phagocyte: phagist-Forms nouns that denote a person who 'feeds on' the first element or part of the word
Although choriocarcinoma is a highly malignant tumour and a life-threatening disease, it is very sensitive to chemotherapy. Virtually all women with non-metastatic disease are cured and retain their fertility; the prognosis is also very good for those with metastatic (spreading) cancer, in the early stages, but fertility may be lost.
A micrograph showing a choriocarcinoma spread to the lung [13] Choriocarcinomas are exceptionally rare which account for 2.1%-3.4% of all OGCTs. [ 14 ] Under gross examination, the syncytiotrophoblast cells are aligned in a plexiform arrangement with the mononucleated cytotrophoblast cells surrounding the foci of the hemorrhage. [ 1 ]
Gestational choriocarcinoma is a form of gestational trophoblastic neoplasia, which is a type of gestational trophoblastic disease (GTD), that can occur during pregnancy. It is a rare disease where the trophoblast , a layer of cells surrounding the blastocyst , undergoes abnormal developments, leading to trophoblastic tumors .
Meaning c̅ (c with an overbar) with (from Latin cum) means with C: cytosine cervical vertebrae: C1: atlas – first cervical vertebra of the spine C2: axis – second cervical vertebra of the spine CA: carcinoma cancer: Ca: calcium carcinoma cancer: CAA: coronary artery aneurysm: c/b: complicated by: CABG: coronary artery bypass graft ...
Angiomatous (vascular) type : This is the most common type of choriocarcinoma. It is distinguished by the presence of numerous small blood vessels. Degenerative type : This is the mature type with degenerative changes. Each type is believed to represent a phase of tumor development. Chorioangioma has no malignant potential.