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Melasma (also known as chloasma faciei, [1]: 854 or the mask of pregnancy [2] when present in pregnant women) is a tan or dark skin discoloration. Melasma is thought to be caused by sun exposure, genetic predisposition, hormone changes, and skin irritation. [ 3 ]
Azelaic acid, which this product is formulated with, is a great over-the-counter (and pregnancy-safe) alternative to prescription hydroquinone, an old-school treatment for melasma. “[Azelaic ...
In short, melasma is a chronic skin condition that appears as darkened areas on the face due to an overproduction of melanin, says Gina Charles, MO, a family physician specializing in skincare. It ...
Estrogen also rises during pregnancy, and that, combined with progesterone, can contribute to the formation of melasma, which appears as dark brown spots or patches.
There are a wide range of depigmenting treatments used for hyperpigmentation conditions, and responses to most are variable. [11]Most often treatment of hyperpigmentation caused by melanin overproduction (such as melasma, acne scarring, liver spots) includes the use of topical depigmenting agents, which vary in their efficacy and safety, as well as in prescription rules.
Azelaic acid is used for treatment of skin pigmentation, including melasma and postinflammatory hyperpigmentation, particularly in those with darker skin types. It has been recommended as an alternative to hydroquinone. [25] As a tyrosinase inhibitor, [5] azelaic acid reduces synthesis of melanin. [26]
Look for a melasma serum or melasma cream (the texture is totally a personal choice) with vitamin C (ideally in the 10 to 20 percent range), tranexamic acid, azelaic acid, arbutin, kojic acid, and ...
One 2017 review found tentative evidence of benefit of tranexamic acid in melasma. [13] Another 2017 review found that evidence to support its use was insufficient. [14] Azelaic acid may be a second-line option for melasma. [15] A number of types of laser treatments have been used in melasma with some evidence of benefit. [16]
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