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In toxicology, the lethal dose (LD) is an indication of the lethal toxicity of a given substance or type of radiation. Because resistance varies from one individual to another, the "lethal dose" represents a dose (usually recorded as dose per kilogram of subject body weight) at which a given percentage of subjects will die.
Toxic: a chemical that has a median lethal concentration (LC 50) in air of more than 200 parts per million (ppm) but not more than 2,000 parts per million by volume of gas or vapor, or more than 2 milligrams per liter but not more than 20 milligrams per liter of mist, fume or dust, when administered by continuous inhalation for 1 hour (or less if death occurs within 1 hour) to albino rats ...
Absolute lethal concentration, LC 100; Absolute lethal dose, LD 100 The most referenced value in the chemical industry is the median lethal dose, or LD50. This is the concentration of substance which resulted in the death of 50% of test subjects (typically mice or rats) in the laboratory.
In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. [1] The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.
AEGL-1 is the airborne concentration above which notable discomfort or irritation could be experienced. However, the effects are not disabling and reversible once exposure stops. AEGL-2 is the airborne concentration above which irreversible or other serious, long-lasting adverse health effects or an impaired ability to escape could be experienced.
The concentration of the anesthetic in blood includes the portion that is undissolved in plasma and the portion that is dissolved (bound to plasma proteins). The more soluble the inhaled anesthetic is in blood compared to in air, the more it binds to plasma proteins in the blood and the higher the blood–gas partition coefficient.
The TLV for chemical substances is defined as a concentration in air, typically for inhalation or skin exposure. Its units are in parts per million (ppm) for gases and in milligrams per cubic meter (mg/m 3 ) for particulates such as dust , smoke and mist .
The lowest-observed-adverse-effect level (LOAEL), or the lowest-observed-adverse-effect concentration (LOAEC), is the lowest concentration or amount of a substance found by experiment or observation that causes an adverse alteration of morphology, function, capacity, growth, development, or lifespan of a target organism distinguished from normal organisms of the same species under defined ...