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High levels of bromide chronically impair the membrane of neurons, which progressively impairs neuronal transmission, leading to toxicity, known as bromism. Bromide has an elimination half-life of 9 to 12 days, which can lead to excessive accumulation. Doses of 0.5 to 1 gram per day of bromide can lead to bromism.
A bromide ion is the negatively charged form (Br ... chronic toxicity from bromide can result in bromism, a syndrome with multiple neurological symptoms.
Methyl bromide is a neurotoxin. Accidental poisonings with methyl bromide have been recorded, but few cases documented the concentrations or duration of exposure. It is practically odorless, even at lethal doses, and can cause headaches, mental disturbances, nausea, vomiting and lung edema.
The bromide anion is not very toxic: a normal daily intake is 2 to 8 milligrams. [75] However, high levels of bromide chronically impair the membrane of neurons, which progressively impairs neuronal transmission, leading to toxicity, known as bromism. Bromide has an elimination half-life of 9 to 12 days, which can lead to excessive accumulation ...
Bromide compounds, especially sodium bromide, remained in over-the-counter sedatives and headache remedies (such as the original formulation of Bromo-Seltzer) in the US until 1975, when bromides were outlawed in all over-the-counter medicines, due to chronic toxicity. [10] Bromide's exceedingly long half life in the body made it difficult to ...
Sodium bromide is an inorganic compound with the formula Na Br. ... In 1975, bromides were removed from drugs in the U.S. such as Bromo-Seltzer due to toxicity.
Most use of ethidium bromide in the laboratory (0.25–1 μg/mL) is below the LD50 dosage, making acute toxicity unlikely. Testing in humans and longer studies in a mammalian system would be required to fully understand the long-term risk ethidium bromide poses to lab workers, but it is clear that ethidium bromide can cause mutations in ...
Theobromine poisoning, also informally called chocolate poisoning or cocoa poisoning, is an overdosage reaction to the xanthine alkaloid theobromine, ...