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Depot MPA (DMPA) and EC/MPA were developed by Upjohn in the 1960s. [12] [13] DMPA (brand name Depo-Provera) was introduced for use as a progestogen-only injectable contraceptive for the first time outside of the United States in 1969 and was subsequently approved for use in birth control in the United States in 1992.
[234] [235] However, in 1992, the medication was finally approved by the FDA, under the brand name Depo-Provera, for use in contraception. [234] A subcutaneous formulation of DMPA was introduced in the United States as a contraceptive under the brand name Depo-SubQ Provera 104 (104 mg/0.65 mL MPA) in December 2004, and subsequently was also ...
Medroxyprogesterone acetate (brand names Depo-Provera, Provera, Depo-subQ Provera 104) [4] – 150 mg (intramuscularly) or 104 mg (subcutaneously) every 3 months [3] Norethisterone enanthate (brand names NET EN, Noristerat, Norigest, Doryxas) [ 5 ] – 200 mg (intramuscularly) every 2 months [ 3 ]
Different forms of birth control have different potential side effects. Not all, or even most, users will experience side effects from a method. The less effective the method, the greater the risk of pregnancy, and the side effects associated with pregnancy. Minimal or no side effects occur with coitus interruptus, fertility awareness-based ...
[1] [46] Other side effects of progestogens may include an increased risk of breast cancer, cardiovascular disease, and blood clots, among others. [2] Some of the side effects of progestogens are due not to their progestogenic activity but rather due to off-target activities (e.g., androgenic activity, glucocorticoid activity ...
Other side effects include breast tenderness/pain, headache, and libido changes. [26] Some fluid retention can occur, but weight gain is minimal. [26] Local injection site reactions have also been reported in 15 to 35% of women. [26] Effects of CICs on coagulation and fibrinolysis are minimal and are not thought to be clinically relevant. [27]
Estradiol cypionate (EC), sold under the brand name Depo-Estradiol among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for trans women, and in hormonal birth control for women. [14] [8] [15] [16] It is given by injection into muscle once every 1 to ...
For some users, these side effects lead them to discontinue use. [23] The most common side effect of the contraceptive implant is irregular bleeding, which includes both reduced and increased levels of bleeding. [24] Other side effects include mood changes and mild insulin resistance. [21]
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