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  2. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    Opioid antagonists remain the standard treatment for respiratory depression following opioid overdose, with naloxone being by far the most commonly used, although the longer acting antagonist nalmefene may be used for treating overdoses of long-acting opioids such as methadone, and diprenorphine is used for reversing the effects of extremely ...

  3. Opiate - Wikipedia

    en.wikipedia.org/wiki/Opiate

    A chart outlining the structural features that define opiates and opioids, including distinctions between semi-synthetic and fully synthetic opioid structures. An opiate is an alkaloid substance derived from opium (or poppy straw). [1]

  4. Narcotic - Wikipedia

    en.wikipedia.org/wiki/Narcotic

    Endogenous opioids (enkephalins, dynorphin, endorphin) do not bind specifically to any particular opioid receptor. Receptor binding of the opioid causes a cascade leading to the channel opening and hyperpolarization of the neuron. The opioid receptors have the following channel types: mu, K + channel; l delta, K + channel; kappa, Ca 2+ channel ...

  5. Opioid epidemic in the United States - Wikipedia

    en.wikipedia.org/wiki/Opioid_epidemic_in_the...

    Opiates such as morphine have been used for pain relief in the United States since the 1800s, and were used during the American Civil War. [58] [59] Opiates soon became known as a wonder drug and were prescribed for a wide array of ailments, even for relatively minor treatments such as cough relief. [60] Bayer began marketing heroin ...

  6. Opioid epidemic - Wikipedia

    en.wikipedia.org/wiki/Opioid_epidemic

    The opioid epidemic, also referred to as the opioid crisis, is the rapid increase in the overuse, misuse/abuse, and overdose deaths attributed either in part or in whole to the class of drugs called opiates/opioids since the 1990s. It includes the significant medical, social, psychological, demographic and economic consequences of the medical ...

  7. List of countries by prevalence of opiates use - Wikipedia

    en.wikipedia.org/wiki/List_of_countries_by...

    This is a list of countries (and some territories) by the annual prevalence of opiates use as percentage of the population aged 15–64 (unless otherwise indicated).. The primary source of information are the World Drug Report 2011 (WDR 2011) and the World Drug Report 2006 (WDR 2006), [1] [2] published by the United Nations Office on Drugs and Crime (UNODC).

  8. 'It's like Game of Thrones': Inside the jockeying for Trump ...

    www.aol.com/news/game-thrones-inside-jockeying...

    The expedited pace, however, has not come without setbacks and intrigue. Trump has long skipped the careful vetting of the backgrounds and financial records of potential picks that most incoming ...

  9. Prescription drug addiction - Wikipedia

    en.wikipedia.org/wiki/Prescription_Drug_Addiction

    Prescription drug addiction is the chronic, repeated use of a prescription drug in ways other than prescribed for, including using someone else’s prescription. [3] [4] A prescription drug is a pharmaceutical drug that may not be dispensed without a legal medical prescription.