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Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively. [8] Endemic iodine deficiency accounts for most hypothyroidism in pregnant women worldwide while chronic autoimmune thyroiditis is the most common cause of hypothyroidism in iodine sufficient parts of the world.
Experts have not reached agreement on whether all pregnant women should be routinely screened for thyroid problems. But, if an underactive thyroid with or without symptoms is found during pregnancy it should be treated to lower the risk of pregnancy problems. An underactive thyroid without symptoms occurs in 2 to 3 in every 100 pregnancies.
Congenital iodine deficiency syndrome (CIDS), also called cretinism, [2] is a medical condition present at birth marked by impaired physical and mental development, due to insufficient thyroid hormone production (hypothyroidism) often caused by insufficient dietary iodine during pregnancy.
Even with appropriate treatment, it may pose risks not only to the mother, but also to the fetus. Thyroid hormones , T4 and TSH , diffuse across the placenta traveling from the mother to fetus for 10–12 weeks before the fetus’s own thyroid gland can begin synthesizing its own thyroid hormones. [ 2 ]
American guidelines recommend that treatment should be considered in people with symptoms of hypothyroidism, detectable antibodies against thyroid peroxidase, a history of heart disease, or are at an increased risk for heart disease if the TSH is elevated but below 10 mIU/L. [8] American guidelines further recommend universal treatment ...
Thyroid diseases are highly prevalent worldwide, [10] [11] [12] and treatment varies based on the disorder. Levothyroxine is the mainstay of treatment for people with hypothyroidism, [13] while people with hyperthyroidism caused by Graves' disease can be managed with iodine therapy, antithyroid medication, or surgical removal of the thyroid ...
One study found that thyroid disorders, such as hypothyroidism (low thyroid hormone production), may decrease the production of estrogen and other hormones. However, the above study's sample size ...
Successful pregnancy outcomes are improved when hypothyroidism is treated. [129] Levothyroxine treatment may be considered at lower TSH levels in pregnancy than in standard treatment. [15] Liothyronine does not cross the fetal blood-brain barrier, so liothyronine (T 3) only or liothyronine + levothyroxine (T 3 + T 4) therapy is not indicated in ...
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