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A 25 mg/mL concentration of progesterone oil for intramuscular injection and a 38 mg/device progesterone intrauterine device (Progestasert) have been discontinued. [ 93 ] An oral combination formulation of micronized progesterone and estradiol in oil-filled capsules (brand name Bijuva) is marketed in the United States for the treatment of ...
Progesterone is used as part of hormone replacement therapy in people who have low progesterone levels, and for other reasons. For purposes of comparison with normal physiological circumstances, luteal phase levels of progesterone are 4 to 30 ng/mL, while follicular phase levels of progesterone are 0.02 to 0.9 ng/mL, menopausal levels are 0.03 to 0.3 ng/mL, and levels of progesterone in men ...
Hydroxyprogesterone caproate (Delalutin, Makena, Makena Preservative Free) – 125 mg/mL, 250 mg/mL; Medroxyprogesterone acetate (Depo-Provera) – 400 mg/mL – approved specifically for the treatment of endometrial/renal cancer; Progesterone (Progesterone) – 50 mg/mL (25 mg/mL discontinued)
On the other hand, a single 50 mg intramuscular injection of progesterone, which is associated with high progesterone levels of approximately 50 ng/mL (or early- to mid-pregnancy levels), [154] [155] [156] resulted in substantial (50–60%) suppression of luteinizing hormone, follicle-stimulating hormone, and testosterone levels in men.
[64] [65] It has also been marketed in the form of 100, 200, 250, 400, and 500 mg oral tablets; 500 and 1,000 mg oral suspensions; and as a 50 mg/mL microcrystalline aqueous suspension for intramuscular injection. [66] [67] A 100 mg/mL microcrystalline aqueous suspension for intramuscular injection was previously available as well. [64]
Available forms of progesterone [sources 1] [a] Route Form Dose ... injection: Oil solution: 2, 5, 10, 20, 25, 50, 100 mg/mL: Proluton [c] Widespread
Estradiol benzoate is and has been available as an oil solution for intramuscular injection provided as vials and ampoules at concentrations of 0.167, 0.2, 0.33, 1, 1.67, 2, 5, 10, 20, and 25 mg/mL. [ 23 ] [ 31 ] [ 8 ] It is also available as a microcrystalline aqueous suspension for intramuscular injection under the brand name Agofollin Depot.
Progesterone ⓘ (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. [1] [13] It belongs to a group of steroid hormones called the progestogens [13] and is the major progestogen in the body.
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