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Acinar adenocarcinoma of the lung is a highly lethal disease. Overall, the five-year survival rates approximate 16% to 22%. Generally, survival is better in all stages for patients with the acinar (or papillary) pattern than it is in patients with the solid pattern, but considerably worse than those with the bronchioloalveolar pattern.
The 2011 consensus describes five subtypes of invasive adenocarcinomas based on the cell pattern that is most predominant. These subtypes are described below: Histopathology of lepidic predominant adenocarcinoma. Acinar pattern. [16] Solid pattern. [17] lepidic predominant [18] acinar predominant [19] papillary predominant [20] micropapillary ...
It tends to arise in the distal bronchioles or alveoli and is defined by a non-invasive growth pattern. This small solitary tumor exhibits pure alveolar distribution (lepidic growth) and lacks any invasion of the surrounding normal lung. If completely removed by surgery, the prognosis is excellent with up to 100% 5-year survival.
Adenocarcinomas are classified as lepidic (growing along the surface of intact alveolar walls), [22] acinar and papillary, or micropapillary and solid pattern. Lepidic adenocarcinomas tend to be least aggressive, while micropapillary and solid pattern adenocarcinomas are most aggressive. [23]
In a string-net liquid, atoms have apparently unstable arrangement, like a liquid, but are still consistent in overall pattern, like a solid. When in a normal solid state, the atoms of matter align themselves in a grid pattern, so that the spin of any electron is the opposite of the spin of all electrons touching it.
It describes how patterns in nature, such as stripes and spirals, can arise naturally from a homogeneous, uniform state. The theory, which can be called a reaction–diffusion theory of morphogenesis, has become a basic model in theoretical biology. [2] Such patterns have come to be known as Turing patterns.
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The resulting photographs of standing wave patterns are striking. Lauterwasser's book focused on creating detailed visual analogues of natural patterns ranging from the distribution of spots on a leopard to the geometric patterns found in plants and flowers, to the shapes of jellyfish and the intricate patterns found on the shell of a tortoise.