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  2. Exemestane - Wikipedia

    en.wikipedia.org/wiki/Exemestane

    Exemestane, sold under the brand name Aromasin among others, is a medication used to treat breast cancer. It is a member of the class of antiestrogens known as aromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive ...

  3. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Refractory metastatic melanoma, childhood acute lymphoblastic leukaemia, chronic myeloid leukaemia in blast crises, neuroblastoma, non-small cell lung cancer and breast cancer. Myelosuppression, neurotoxicity and paralytic ileus. Vinflunine: IV: As above. Bladder cancer: As per vinblastine. Vinorelbine: IV: As above. Breast cancer and non-small ...

  4. Non steroidal aromatase inhibitors - Wikipedia

    en.wikipedia.org/wiki/Non_steroidal_aromatase...

    AIs inhibit the enzyme aromatase that converts testosterone to estrogen and that is used clinically in treatments of breast cancer in postmenopausal women. Currently, two types of NSAIs are used for breast cancer, anastrozole and letrozole. They are used as first-line therapy in metastatic breast cancer and also in adjuvant treatment. [1]

  5. Anastrozole - Wikipedia

    en.wikipedia.org/wiki/Anastrozole

    Anastrozole, sold under the brand name Arimidex among others, is an antiestrogenic medication used in addition to other treatments for breast cancer. [6] [7] Specifically it is used for hormone receptor-positive breast cancer. [7] It has also been used to prevent breast cancer in those at high risk. [7] It is taken by mouth. [7]

  6. Aromatase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Aromatase_inhibitor

    Aromatase inhibitors (AIs) are a class of drugs used in the treatment of breast cancer in postmenopausal women and in men, [1] [2] and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when supplementing testosterone exogenously. They may also be used for chemoprevention in women at high risk for breast cancer.

  7. High-dose chemotherapy and bone marrow transplant - Wikipedia

    en.wikipedia.org/wiki/High-dose_chemotherapy_and...

    High-dose chemotherapy and bone marrow transplant (HDC/BMT), also high-dose chemotherapy with autologous bone marrow transplant (HDC/ABMT or just ABMT), was an ineffective treatment regimen for metastatic breast cancer, and later high-risk breast cancer, that was considered promising during the 1980s and 1990s.

  8. AstraZeneca's breast cancer drug combination fails in late ...

    www.aol.com/news/astrazenecas-breast-cancer-drug...

    The trial, known as CAPItello-290, was testing whether the drug combination improved overall survival in patients with inoperable or metastatic triple-negative breast cancer versus the older and ...

  9. Steroidal aromatase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Steroidal_aromatase_inhibitor

    Steroidal aromatase inhibitors are a class of drugs that are mostly used for treating breast cancer in postmenopausal women. High levels of estrogen in breast tissue increases the risk of developing breast cancer and the enzyme aromatase is considered to be a good therapeutic target when treating breast cancer due to it being involved in the final step of estrogen biosynthetic pathway and also ...

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