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Estrogen is associated with edema, including facial and abdominal swelling. Melanin. Estrogen is known to cause darkening of skin, especially in the face and areolae. [38] Pale skinned women will develop browner and yellower skin during pregnancy, as a result of the increase of estrogen, known as the "mask of pregnancy". [39]
The volumes of sexually dimorphic brain structures in transgender women were found to change and approximate typical female brain structures when exposed to estrogen concomitantly with androgen deprivation over a period of months, [31] suggesting that estrogen and/or androgens have a significant part to play in sex differentiation of the brain ...
Estrogenic fat is a feminine secondary sex characteristic which develops at puberty and is maintained by estradiol throughout a woman's fertile years. A special form of estrogenic fat is the iliac (hip) fat layer, which normally occurs below the iliac crest in females of childbearing age.
Aromatase (EC 1.14.14.14), also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens. It is CYP19A1 , a member of the cytochrome P450 superfamily, which are monooxygenases that catalyze many reactions involved in steroidogenesis .
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They have important effects in many tissues in the body, including in the female reproductive system (uterus, vagina, and ovaries), the breasts, bone, fat, the liver, and the brain among others. [1] Unlike other medications like progestins and anabolic steroids, estrogens do not have other hormonal activities. [ 1 ]
Gynoid fat contributes toward the female body shape that girls begin to develop at puberty; it is stored in the hips, thighs and bottom. [7] This process is modulated by estrogen, the female sex hormone, causing the female form to store higher levels of fat than the male form, which is affected primarily by testosterone.
Conversely, “with too much testosterone, women often have acne, too much hair on the body, hair loss on the head, high blood pressure, elevated cholesterol, skipped cycles, or problems ...