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Clubbing is associated with lung cancer, lung infections, interstitial lung disease, cystic fibrosis, or cardiovascular disease. [5] Clubbing may also run in families, [5] and occur unassociated with other medical problems. [6] [7] Clubbing has been recognized as a sign of disease since the time of Hippocrates. [5]
At present, the specific cause of shell nail syndrome is unknown. American doctors Chalmers E. Cornelius and Walter B. Shelley first characterized the morphogenesis of the condition in a 1967 Archives of Dermatology publication, stating: "this disorder can be explained by the production of a curved nail by a normal nail matrix which grows out as a shell to thus form a roof over the atrophic ...
Nail clubbing - nails that curve down around the fingertips with nailbeds that bulge is associated with oxygen deprivation and lung, heart, or liver disease. Koilonychia - spooning, or nails that grow upwards. Associated with iron-deficiency anaemia or vitamin B 12 deficiency. [citation needed] Pitting of the nails is associated with psoriasis.
The nails are markedly thickened with yellow to yellow-green discoloration of the nails. [1]: 792 [6] They grow slowly, at a rate of 0.25 mm/week or less. The nails may have ridges and increased side-to-side curvature, reduction of the white crescent and detachment of the nail from the nailbed. [5] These nail abnormalities may also change over ...
Lung transplantation is the only therapeutic option available in severe cases. A lung transplant can improve the patient's quality of life. [30] Immunosuppressive drugs can also be considered. These are sometimes prescribed to slow the processes that lead to fibrosis. Some types of lung fibrosis respond to corticosteroids, such as prednisone. [29]
One study found that only 37% of the patient sample studied (mean age 32±14 years; M 45%) had normal lung function. [23] Spontaneous pneumothorax is common. [24] In spontaneous unilateral pneumothorax, air escapes from a lung and occupies the pleural space between the chest wall and a lung. The lung becomes partially compressed or collapsed.
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Terry's nails is a physical condition in which a person's fingernails or toenails [1]: ... Eighty percent of patients with severe liver disease have Terry's nails, ...