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Folate deficiency, also known as vitamin B 9 deficiency, is a low level of folate and derivatives in the body. [1] This may result in megaloblastic anemia in which red blood cells become abnormally large, and folate deficiency anemia is the term given for this medical condition. [3] Signs of folate deficiency are often subtle. [4]
Nutritional causes are vitamin and mineral deficiencies and non-nutritional causes include infections. The number one cause of this type of anemia, however, is iron deficiency. [12] An insufficient intake of iron, Vitamin B12, and folic acid impairs the bone marrow function. The lack of iron within a person's body can also stem from ulcer bacteria.
Iron deficiency anemia can intensify symptoms of fatigue and shortening of breath, and can cause cold sensitivity, hair loss, paleness to the skin and nail changes, says Cunningham. It has also ...
Causes of decreased production include iron deficiency, folate deficiency, vitamin B 12 deficiency, thalassemia and a number of bone marrow tumors. [1] Causes of increased breakdown include genetic disorders such as sickle cell anemia , infections such as malaria , and certain autoimmune diseases like autoimmune hemolytic anemia .
In fact, over a third of U.S. females ages 12 to 21 are iron-deficient, with heavy periods, pregnancy and the postpartum period being major causes of iron deficiency anemia.
An analysis of data from more than 8,000 adults in the U.S. revealed that 14% had low iron blood levels, a condition known as absolute iron deficiency, while 15% had the right iron levels but ...
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