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The three-dimensional structure of alpha-bungarotoxin, an alpha-neurotoxin from the venom of Bungarus multicinctus. Gold links indicate disulfide bonds. From 1] α-Neurotoxins are a group of neurotoxic peptides found in the venom of snakes in the families Elapidae and Hydrophiidae. They can cause paralysis, respiratory failure, and death.
Neurotoxins inhibit neuron control over ion concentrations across the cell membrane, [6] or communication between neurons across a synapse. [13] Local pathology of neurotoxin exposure often includes neuron excitotoxicity or apoptosis [14] but can also include glial cell damage. [15]
The term neurotoxicity implies the involvement of a neurotoxin; however, the term neurotoxic may be used more loosely to describe states that are known to cause physical brain damage, but where no specific neurotoxin has been identified. [citation needed]
Alpha-neurotoxins are a large group; over 100 postsynaptic neurotoxins having been identified and sequenced. [12] α-neurotoxins attack the Nicotinic acetylcholine receptors of cholinergic neurons. They mimic the shape of the acetylcholine molecule, and so fit into the receptors, where they block the ACh flow, leading to a feeling of numbness ...
Pages in category "Neurotoxins" The following 200 pages are in this category, out of approximately 230 total. This list may not reflect recent changes.
Domoic acid is a neurotoxin released by Pseudo-nitzschia, a common phytoplankton species found in coastal waters. Sea lions — and other marine mammals — become poisoned when they eat large ...
α-Bungarotoxin is one of the bungarotoxins, components of the venom of the elapid Taiwanese banded krait snake (Bungarus multicinctus).It is a type of α-neurotoxin, a neurotoxic protein that is known to bind competitively and in a relatively irreversible manner to the nicotinic acetylcholine receptor found at the neuromuscular junction, causing paralysis, respiratory failure, and death in ...
The pesticides are neurotoxins and are the most widely used class of insecticides in the world, lawmakers have said. The Democrat-controlled Vermont legislature may consider overriding the ...