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  2. Drug of last resort - Wikipedia

    en.wikipedia.org/wiki/Drug_of_last_resort

    Such placement may result from a multitude of considerations, including greater efficacy of other agents, socioeconomic considerations, availability issues, unpleasant side effects or similar issues relating to patient tolerance. Some experimental therapies might also be called drugs of last resort when administered following the failure of all ...

  3. Vancomycin - Wikipedia

    en.wikipedia.org/wiki/Vancomycin

    Serum vancomycin levels may be monitored in an effort to reduce side effects, [27] but the value of such monitoring has been questioned. [28] Peak and trough levels are usually monitored, and for research purposes the area under the concentration curve is also sometimes used. [29] Toxicity is best monitored by looking at trough values. [29]

  4. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    The procedure is to take the child's weight in pounds, divide by 150 lb, and multiply the fractional result by the adult dose to find the equivalent child dosage.For example, if an adult dose of medication calls for 30 mg and the child weighs 30 lb, divide the weight by 150 (30/150) to obtain 1/5 and multiply 1/5 times 30 mg to get 6 mg.

  5. Glycopeptide antibiotic - Wikipedia

    en.wikipedia.org/wiki/Glycopeptide_antibiotic

    Some other side-effects of vancomycin are nephrotoxicity including kidney failure and interstitial nephritis, blood disorders including neutropenia, and deafness, which is reversible once therapy has stopped. Over 90% of the dose is excreted in the urine, therefore there is a risk of accumulation in patients with renal impairment, so ...

  6. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    As one can see, it would take many days for the total amount of drug within the body to come close to 1 gram (1000 mg) and achieve its full therapeutic effect. For a drug such as this, a doctor might prescribe a loading dose of one gram to be taken on the first day. That immediately gets the drug's concentration in the body up to the ...

  7. 5 Phrases a Child Psychologist Is Begging Parents and ...

    www.aol.com/5-phrases-child-psychologist-begging...

    In the life of your child, you easily exchange thousands of words every day, or at the very least every week. And while many of these conversations may seem normal and even fairly inconsequential ...

  8. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    Classically, for clinical indications of an approved drug, TI refers to the ratio of the dose of the drug that causes adverse effects at an incidence/severity not compatible with the targeted indication (e.g. toxic dose in 50% of subjects, TD 50) to the dose that leads to the desired pharmacological effect (e.g. efficacious dose in 50% of ...

  9. 14 Things That Might Be Causing Pain in Your Lower Left Abdomen

    www.aol.com/14-things-might-causing-pain...

    Ovulation pain (mittelschmerz): Mid-cycle pain during ovulation, often on one side. Menstrual cramps: Commonly experienced during menstruation and can radiate to the lower abdomen.

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