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  2. Acute intermittent porphyria - Wikipedia

    en.wikipedia.org/wiki/Acute_intermittent_porphyria

    The acute attacks classically present with dark-red photosensitive urine (often called port-wine urine), but this is a nonspecific symptom. [12] Physical examination often shows no abnormalities. [13] Hyponatremia is the most common electrolyte abnormality during acute attacks, occurring in 40% of patients and presenting as SIADH. [13]

  3. Porphyria - Wikipedia

    en.wikipedia.org/wiki/Porphyria

    Porphyria / p ɔːr ˈ f ɪr i ə / is a group of disorders in which substances called porphyrins build up in the body, adversely affecting the skin or nervous system. [1] The types that affect the nervous system are also known as acute porphyria, as symptoms are rapid in onset and short in duration. [1]

  4. Gliquidone - Wikipedia

    en.wikipedia.org/wiki/Gliquidone

    Diabetes mellitus type 1; Diabetic ketoacidosis; Patients that underwent removal of the pancreas; Acute porphyria; Severe liver disease accompanying with liver insufficiency; Several conditions (e.g., infectious diseases or major surgical intervention), when insulin administration is required; Pregnancy or breastfeeding [2]

  5. Porphobilinogen deaminase - Wikipedia

    en.wikipedia.org/wiki/Porphobilinogen_deaminase

    The most well-known health issue involving porphobilinogen deaminase is acute intermittent porphyria, an autosomal dominant genetic disorder where insufficient hydroxymethylbilane is produced, leading to a build-up of porphobilinogen in the cytoplasm. This is caused by a gene mutation that, in 90% of cases, causes decreased amounts of enzyme.

  6. Erythropoietic protoporphyria - Wikipedia

    en.wikipedia.org/wiki/Erythropoietic_protoporphyria

    Erythropoietic protoporphyria (or commonly called EPP) is a form of porphyria, which varies in severity and can be very painful.It arises from a deficiency in the enzyme ferrochelatase, leading to abnormally high levels of protoporphyrin in the red blood cells (erythrocytes), plasma, skin, and liver. [2]

  7. Hereditary coproporphyria - Wikipedia

    en.wikipedia.org/wiki/Hereditary_coproporphyria

    Hereditary coproporphyria (HCP) is a disorder of heme biosynthesis, classified as an acute hepatic porphyria. [1] HCP is caused by a deficiency of the enzyme coproporphyrinogen oxidase, coded for by the CPOX gene, and is inherited in an autosomal dominant fashion, although homozygous individuals have been identified.

  8. Are Diabetes Drugs Really Safe (& Reliable) for Weight Loss?

    www.aol.com/diabetes-drugs-really-safe-reliable...

    GLP-1 drugs for weight loss and type 2 diabetes include dulaglutide, liraglutide, and semaglutide. GIP/GLP-1s. These are dual-acting, meaning they target two receptors in the body: gastric ...

  9. Aminolevulinic acid dehydratase deficiency porphyria - Wikipedia

    en.wikipedia.org/wiki/Aminolevulinic_acid_de...

    Aminolevulinic acid dehydratase deficiency porphyria (also known as Doss porphyria, [1] plumboporphyria, [1] or ADP [2]) is an extremely rare autosomal recessive metabolic disorder that results from inappropriately low levels of the enzyme delta-aminolevulinic acid dehydratase (), which is required for normal heme synthesis.

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