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Values are K i (nM). The smaller the value, the more strongly the drug binds to the site. The smaller the value, the more strongly the drug binds to the site. Dibenzepin acts as a selective norepinephrine reuptake inhibitor (NRI), with similar potency to that of imipramine . [ 10 ]
Like many other psychedelics, aleph is a partial agonist at the 5-HT 2A receptor (EC 50 = 10 nM). [2] It has weak MAO-A inhibitory activity with an IC 50 of 5.2 μM. For reference, amphetamine has an IC 50 of 11 μM and 4-methylthioamphetamine has a value of 0.2 μM. [3] A lower number indicates stronger inhibition.
Ganesha (2,5-dimethoxy-3,4-dimethylamphetamine) is a lesser-known psychedelic drug.It is also a substituted amphetamine.It was first synthesized by Alexander Shulgin. [citation needed] In his book PiHKAL, the dosage range is listed as 24–32 mg. [1] The drug is usually taken orally, although other routes such as rectally may also be used.
The NBOMe drugs are highly potent and selective agonists of the serotonin 5-HT 2 receptors, including of the 5-HT 2A, 5-HT 2B, and 5-HT 2C receptors. [1] [3] [12] [13] However, they are much less potent and efficacious at the serotonin 5-HT 2B receptor compared to the serotonin 5-HT 2A and 5-HT 2C receptors. [3]
2C-B (4-bromo-2,5-dimethoxyphenethylamine), also known as Nexus, is a synthetic psychedelic drug of the 2C family, mainly used as a recreational drug. [2] [1] [4] It was first synthesized by Alexander Shulgin in 1974 for use in psychotherapy.
Chlorprothixene's principal indications are the treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occurring as part of bipolar disorders.. Other uses are pre- and postoperative states with anxiety and insomnia, severe nausea / emesis (in hospitalized patients), the amelioration of anxiety and agitation due to use of selective serotonin reuptake inhibitors for depression ...
C 11 H 16 N 2 O 4: Molar mass: 240.259 g·mol −1 ... Alexander Shulgin lists a dosage of DON as being 3-4.5 mg orally with amphetamine-like stimulation lasting 8 ...
The full name of the chemical is 2-(2,5-dimethoxy-4-nitro phenyl)ethanamine. Salts of 2C-N have a bright yellow to orange color due to the presence of the nitro group, [ citation needed ] unlike all other members of the 2C family in which the salts are white.