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The latter is suspected to help S. aureus penetrate human tissue. [9] A higher mortality is linked with multispecies biofilms. [46] Staphylococcus aureus biofilm is the predominant cause of orthopedic implant-related infections, but is also found on cardiac implants, vascular grafts, various catheters, and cosmetic surgical implants.
S. aureus can cause a range of illnesses from minor skin infections to Staphylococcus aureus food poisoning enteritis. Since humans are the primary source, cross-contamination is the most common way the microorganism is introduced into foods. Foods at high risks are those prepared in large quantities. Staphylococcus aureus is a true food ...
The first S. aureus genomes to be sequenced were those of N315 and Mu50, in 2001. Many more complete S. aureus genomes have been submitted to the public databases, making it one of the most extensively sequenced bacteria. The use of genomic data is now widespread and provides a valuable resource for researchers working with S. aureus.
In humans, Staphylococcus aureus is part of the normal microbiota present in the upper respiratory tract, [2] and on skin and in the gut mucosa. [3] However, along with similar bacterial species that can colonize and act symbiotically, they can cause disease if they begin to take over the tissues they have colonized or invade other tissues; the ...
S. saprophyticus, another coagulase-negative species that is part of the normal vaginal flora, is predominantly implicated in uncomplicated lower genitourinary tract infections in young sexually active women. [9] Other staphylococcal species have been implicated in human infections, notably S. lugdunensis, S. schleiferi, and S. caprae.
Staphylococcus pseudintermedius is a gram-positive spherically shaped bacterium of the genus Staphylococcus [1] found worldwide. [2] It is primarily a pathogen for domestic animals, [3] [4] but has been known to affect humans as well. [5]
Cultures of human lung epithelial cells incubated with anti-alpha-toxin and infected with S. aureus showed marked reductions in cellular damage when compared to control cells. As many strains of S. aureus are proving to be resistant to most available antibiotics, specific targeting of virulence factors with antibodies may be the next step to ...
Even though S. aureus was isolated from mucosal sites in the patients, bacteria could not be isolated from the blood, cerebrospinal fluid, or urine, raising suspicion that a toxin was involved. The authors of the study noted reports of similar staphylococcal illnesses had appeared occasionally as far back as 1927, but the authors at the time ...