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  2. Elevated transaminases - Wikipedia

    en.wikipedia.org/wiki/Elevated_transaminases

    Mild transaminesemia refers to levels up to 250 U/L. [1] Drug-induced increases such as that found with the use of anti-tuberculosis agents such as isoniazid are limited typically to below 100 U/L for either ALT or AST. Muscle sources of the enzymes, such as intense exercise, are unrelated to liver function and can markedly increase AST and ALT ...

  3. List of SJS-inducing substances - Wikipedia

    en.wikipedia.org/wiki/List_of_SJS-inducing...

    This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .

  4. Apalutamide - Wikipedia

    en.wikipedia.org/wiki/Apalutamide

    [2] [11] [12] [10] [13] Rarely, it can cause seizures. [ 2 ] [ 10 ] The medication has a high potential for drug interactions . [ 2 ] [ 10 ] Apalutamide is an antiandrogen , and acts as an antagonist of the androgen receptor , the biological target of androgens like testosterone and dihydrotestosterone .

  5. Hepatotoxicity - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxicity

    Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents.

  6. Lists of drugs - Wikipedia

    en.wikipedia.org/wiki/Lists_of_drugs

    Many drugs have more than one name and, therefore, the same drug may be listed more than once. Brand names and generic names are differentiated by capitalizing brand names. See also the list of the top 100 bestselling branded drugs , ranked by sales.

  7. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Polypharmacy is most commonly defined as the use of five or more medications daily by an individual. [6] However, the definition of polypharmacy is still debated and can vary from two to 11 concurrent medications. [6] Any drug: Cannabis: Amp joint [7] Any drug: Nicotine: Cooler [5] Any β-Carboline containing plant (e.g. Banisteriopsis caapi or ...

  8. Fenfluramine - Wikipedia

    en.wikipedia.org/wiki/Fenfluramine

    The suggested mechanism by which fenfluramine causes damage is through over or inappropriate stimulation of these receptors leading to inappropriate valve cell division. Supporting this idea is the fact that this valve abnormality has also occurred in patients using other drugs that act on 5-HT 2B receptors.

  9. Darolutamide - Wikipedia

    en.wikipedia.org/wiki/Darolutamide

    Darolutamide, sold under the brand name Nubeqa, is an antiandrogen medication which is used in the treatment of non-metastatic castration-resistant prostate cancer in men. [8] [4] [5] [9] [10] It is specifically approved to treat non-metastatic castration-resistant prostate cancer (nmCRPC) in conjunction with surgical or medical castration. [4]