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  2. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    Furthermore, while depression and anxiety are frequently comorbid, dissociation of the two in animal models is difficult to achieve. [128] Pharmacological assessment of validity is frequently disconnected from clinical pharmacotherapeutics in that most screening tests assess acute effects, while antidepressants normally take a few weeks to work ...

  3. Tripartite Model of Anxiety and Depression - Wikipedia

    en.wikipedia.org/wiki/Tripartite_Model_of...

    Watson and Clark (1991) proposed the Tripartite Model of Anxiety and Depression to help explain the comorbidity between anxious and depressive symptoms and disorders. [1] This model divides the symptoms of anxiety and depression into three groups: negative affect, positive affect and physiological hyperarousal.

  4. Central nervous system depression - Wikipedia

    en.wikipedia.org/wiki/Central_nervous_system...

    Central nervous system (CNS) depression is a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death. It is the result of inhibited or suppressed brain activity .

  5. Psychophysiology - Wikipedia

    en.wikipedia.org/wiki/Psychophysiology

    Psychophysiology measures exist in multiple domains; reports, electrophysiological studies, studies in neurochemistry, neuroimaging and behavioral methods. [5] Evaluative reports involve participant introspection and self-ratings of internal psychological states or physiological sensations, such as self-report of arousal levels on the self-assessment manikin, [6] or measures of interoceptive ...

  6. Fatigue - Wikipedia

    en.wikipedia.org/wiki/Fatigue

    Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...

  7. Allostatic load - Wikipedia

    en.wikipedia.org/wiki/Allostatic_load

    Homeostasis is the regulation of physiological processes, whereby systems in the body respond to the state of the body and to the external environment. [18] The relationship between allostasis and allostatic load is the concept of anticipation. Anticipation can drive the output of mediators. Examples of mediators include hormones and cortisol.

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