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Minoxidil is a prodrug that is converted by sulfation via the sulfotransferase enzyme SULT1A1 to its active form, minoxidil sulfate. The effect of minoxidil is mediated by adenosine , which triggers intracellular signal transduction via both adenosine A1 receptors and two sub-types of adenosine A2 receptors ( A 2A and A 2B receptors). [ 26 ]
Minoxidil (brand name Rogaine®) is a non-prescription topical medication that promotes hair growth and regrowth by restarting the growth phase in dormant hair follicles.
Rogaine, which is well-known for treating hair loss, is a brand name drug that has minoxidil as the active ingredient. But minoxidil is also sold in its generic forms by various brands, including ...
Two main factors cause male pattern baldness: ... Minoxidil (the active ingredient in Rogaine®) is a topical, over-the-counter medication.
Minoxidil sulfate, also known as minoxidil sulfate ester or minoxidil N-O-sulfate, is an active metabolite of minoxidil (Rogaine, Loniten, others) and is the active form of this agent. [ 1 ] [ 2 ] Minoxidil acts as a prodrug of minoxidil sulfate. [ 1 ]
Minoxidil, applied topically, is widely used for the treatment of hair loss. It may be effective in helping promote hair growth in both men and women with androgenic alopecia . [ 20 ] [ 21 ] About 40% of men experience hair regrowth after 3–6 months. [ 22 ]
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