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Steroid-induced osteoporosis is osteoporosis arising from the use of glucocorticoids (a class of steroid hormones) analogous to Cushing's syndrome but involving mainly the axial skeleton. The synthetic glucocorticoid prescription drug prednisone is a main candidate after prolonged intake.
Causes: Medications related to cancer therapy, and osteoporosis in combination with dental surgery: Risk factors: Duration of anti-resorptive or anti-angiogenic drugs, intravenous vs by-mouth: Diagnostic method: Exposed bone >8 weeks: Differential diagnosis: Osteomyelitis, Osteoradionecrosis: Prevention: No definitive. Drug holiday for some ...
The US National Osteoporosis Foundation recommends pharmacologic treatment for patients with hip or spine fracture thought to be related to osteoporosis, those with BMD 2.5 SD or more below the young normal mean (T-score -2.5 or below), and those with BMD between 1 and 2.5 SD below normal mean whose 10-year risk, using FRAX, for hip fracture is ...
Inflammatory arthritis can sometimes cause symptoms in parts of the body other than the joints, like the eyes, heart, or lungs. As arthritis progresses, joint damage can get worse.
Anticonvulsants are also increasingly being used in the treatment of bipolar disorder [2] [3] and borderline personality disorder, [4] since many seem to act as mood stabilizers, and for the treatment of neuropathic pain. [5] Anticonvulsants suppress the excessive rapid firing of neurons during seizures. [6]
Recent research has found that people with rheumatoid arthritis appear to have a higher risk of neurodegenerative conditions. The risk may be influenced by systemic inflammation.
Further, the more precise terminology clearly distinguishes the condition from full-blown Cushing's syndrome, which is extremely broad regarding the causes (endogenous or exogenous, pituitary or adrenal) and the multitude of symptoms (ranging from skin disorders to osteoporosis), and from hypercortisolemia, which identifies neither the source ...
A number of diseases can cause bone pain, including the following: Endocrine, such as hyperparathyroidism, osteoporosis, kidney failure. [7]Gastrointestinal or systemic, such as celiac disease and non-celiac gluten sensitivity (both often occur without obvious digestive symptoms), inflammatory bowel disease (including Crohn's disease and ulcerative colitis).
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