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In general, if an increase of x percent is followed by a decrease of x percent, and the initial amount was p, the final amount is p (1 + 0.01 x)(1 − 0.01 x) = p (1 − (0.01 x) 2); hence the net change is an overall decrease by x percent of x percent (the square of the original percent change when expressed as a decimal number).
Fold change is a measure describing how much a quantity changes between an original and a subsequent measurement. It is defined as the ratio between the two quantities; for quantities A and B the fold change of B with respect to A is B/A.
A number-line visualization of the algebraic addition 2 + 4 = 6. A "jump" that has a distance of 2 followed by another that is long as 4, is the same as a translation by 6. A number-line visualization of the unary addition 2 + 4 = 6. A translation by 4 is equivalent to four translations by 1.
The modern study of number theory in its abstract form is largely attributed to Pierre de Fermat and Leonhard Euler. The field came to full fruition with the contributions of Adrien-Marie Legendre and Carl Friedrich Gauss. [17] Many easily stated number problems have solutions that require sophisticated methods, often from across mathematics.
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