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The PRISMA flow diagram, depicting the flow of information through the different phases of a systematic review. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) is an evidence-based minimum set of items aimed at helping scientific authors to report a wide array of systematic reviews and meta-analyses, primarily used to assess the benefits and harms of a health care ...
Meta-analysis leads to a shift of emphasis from single studies to multiple studies. It emphasizes the practical importance of the effect size instead of the statistical significance of individual studies. This shift in thinking has been termed "meta-analytic thinking". The results of a meta-analysis are often shown in a forest plot.
In 1966, an early meta-research paper examined the statistical methods of 295 papers published in ten high-profile medical journals. [3] It found that "in almost 73% of the reports read ... conclusions were drawn when the justification for these conclusions was invalid." Meta-research in the following decades found many methodological flaws ...
Due to the expansion of the published research output, new quantitative methods for literature surveys have been developed under the label of meta-analysis or meta-science. These rely on the assumption that quantitative results and the details of the experimental and observational framework are sound (such as the size or the composition of the ...
Meta-theoretical investigations are part of the philosophy of science. [5] The topic of metascience is an attempt to use scientific knowledge to improve the practice of science itself. The study of metatheory became widespread during the 20th century after its application to various topics, including scientific linguistics and its concept of ...
A systematic review is a scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. [1] A systematic review extracts and interprets data from published studies on the topic (in the scientific literature), then analyzes, describes, critically appraises and summarizes interpretations into a refined evidence-based ...
A meta-regression can be classified in the same way—meta-regression and network meta-regression—depending on the number of distinct treatments in the regression analysis. Meta-analysis (and meta-regression) is often placed at the top of the evidence hierarchy provided that the analysis consists of individual participant data of randomized ...
Multiverse analysis is a scientific method that specifies and then runs a set of plausible alternative models or statistical tests for a single hypothesis. [1] It is a method to address the issue that the "scientific process confronts researchers with a multiplicity of seemingly minor, yet nontrivial, decision points, each of which may introduce variability in research outcomes". [2]