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Skin grafting is a surgical procedure where a piece of healthy skin, also known as the donor site, is taken from one body part and transplanted to another, often to cover damaged or missing skin. [12] Before surgery, the location of the donor site would be determined, and patients would undergo anesthesia. [13]
Damaged sweat and sebaceous glands, hair follicles, muscle cells, and nerves are seldom repaired. They are usually replaced by the fibrous tissue. The result is the formation of an inflexible, fibrous scar tissue. Human skin cells are capable of repairing UV-induced DNA damages by the process of nucleotide excision repair. [2]
Skin grafting often takes place after serious injuries when some of the body's skin is damaged. Surgical removal (excision or debridement) of the damaged skin is followed by skin grafting. The grafting serves two purposes: reducing the course of treatment needed (and time in the hospital), and improving the function and appearance of the area ...
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Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
Skin expansion is a common surgical procedure to grow extra skin through controlled mechanical overstretch. It creates skin that matches the color, texture, and thickness of the surrounding tissue, while minimizing scars and risk of rejection. [1] When skin is stretched beyond its physiological limit, mechanotransduction pathways
Following an acute injury, the proximal tubule is damaged more, and the injured epithelial cells slough off the basement membrane of the nephron. The surviving epithelial cells, however, undergo migration, dedifferentiation, proliferation, and redifferentiation to replenish the epithelial lining of the proximal tubule after injury.
Skin: V-plasty · VY-plasty · W-plasty · Z-plasty: Escharotomy: Skin biopsy: Other/ungrouped Abdominoplasty · Hernioplasty · Frenuloplasty · Z-plasty: Diverticulectomy · Frenectomy · Hemorrhoidectomy · Mastoidectomy · Thrombectomy · Embolectomy · Ganglionectomy · Lobectomy · Myomectomy · Panniculectomy