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A meta-analysis of such expression profiles was performed to derive novel conclusions and to validate the known findings. [148] Meta-analysis of whole genome sequencing studies provides an attractive solution to the problem of collecting large sample sizes for discovering rare variants associated with complex phenotypes.
A meta-regression can be classified in the same way—meta-regression and network meta-regression—depending on the number of distinct treatments in the regression analysis. Meta-analysis (and meta-regression) is often placed at the top of the evidence hierarchy provided that the analysis consists of individual participant data of randomized ...
In medical research, an umbrella review is a review of systematic reviews or meta-analyses. [1] [2] [3] They may also be called overviews of reviews, reviews of reviews, summaries of systematic reviews, or syntheses of reviews. [1]
This measure of effect has greater precision (less uncertainty) than the individual studies, but it may be biased by differences between the studies in study design, the type of evidence, or other key characteristics. [4] In qualitative research, methods of synthesis include narrative synthesis and meta-ethnography. Narrative synthesis allows ...
In an IPD meta-analysis, patient-level data from multiple studies or settings are combined to address a certain research question. IPD meta-analyses tend to be common for large-scale and international projects, and they are less limited than aggregate data (AD) meta-analyses in terms of the availability and quality of data they can use. [2]
Iranian authorities have detained a young woman who was seen walking around a university in Tehran in her underwear, according to video shared on social media and state news agencies, in what ...
The jury's out as to whether the Federal Reserve will cut interest rates a third time before the year's end, yet it's a fact that if you haven't yet moved your money to a high-yield savings ...
The main statistical analysis is the mean analysis, which consists in calculating the mean of the voxel values in the different studies. This mean is weighted by the inverse of the variance and accounts for inter-study heterogeneity (QH maps). [2] Subgroup analyses are mean analyses applied to groups of studies to allow the study of heterogeneity.