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Diabetic retinopathy (DR) is a microvascular disorder caused by vision-threatening damage to the retina, a long-term sequela of diabetes mellitus. [1] DR is the most common microvascular complication in diabetic patients and the leading global cause of vision loss in working middle-aged adults.
Diabetic retinopathy (DR) is a major complication of diabetes mellitus (DM), which remains a leading cause of visual loss in working-age populations. The diagnosis of DR is made by clinical manifestations of vascular abnormalities in the retina.
Diabetic retinopathy (DR) is a microvascular disorder occurring due to the long-term effects of diabetes mellitus. Diabetic retinopathy may lead to vision-threatening damage to the retina, eventually leading to blindness.
Diabetic retinopathy represents microvascular end-organ damage as a result of diabetes. It ranges from non-proliferative diabetic retinopathy (NPDR) and its stages to proliferative diabetic retinopathy (PDR). As the disease progresses, associated diabetic macular edema (DME) may also become apparent.
Here, we present a review of the current understanding and new insights into pathophysiology in DR, as well as clinical treatments for DR patients. Recent laboratory findings and related clinical trials are also reviewed.
Vision loss in diabetic retinopathy (DR) is ascribed primarily to retinal vascular abnormalities—including hyperpermeability, hypoperfusion, and neoangiogenesis—that eventually lead to anatomical and functional alterations in retinal neurons and ...
Diabetic Retinopathy - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the Merck Manuals - Medical Professional Version.
We have reviewed different pathological aspects of diabetic retinopathy and its underlying mechanism of occurrence. In this review, we aim to provide an in-depth understanding and illustration of the progression of diabetic retinopathy, its pathophysiology, epidemiology, and prospective therapeutic targets.
With increasing duration of diabetes or with increasing age since its onset, there is a higher risk of developing diabetic retinopathy and its complications, including diabetic macular edema or proliferative diabetic retinopathy.
Diabetic retinopathy, a major cause of blindness in developed countries, is characterised by hyperglycaemia, basement membrane thickening, pericyte loss, microaneurysms, IRMA and preretinal...