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  2. Nussinov algorithm - Wikipedia

    en.wikipedia.org/wiki/Nussinov_algorithm

    The Nussinov algorithm is a nucleic acid structure prediction algorithm used in computational biology to predict the folding of an RNA molecule that makes use of dynamic programming principles. [1] The algorithm was developed by Ruth Nussinov in the late 1970s.

  3. Nucleic acid structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_structure

    Double-stranded RNA forms an A-type helical structure, unlike the common B-type conformation taken by double-stranded DNA molecules. The secondary structure of RNA consists of a single polynucleotide. Base pairing in RNA occurs when RNA folds between complementarity regions. Both single- and double-stranded regions are often found in RNA molecules.

  4. RNA - Wikipedia

    en.wikipedia.org/wiki/RNA

    In 1956 Alex Rich and David Davies hybridized two separate strands of RNA to form the first crystal of RNA whose structure could be determined by X-ray crystallography. [ 77 ] The sequence of the 77 nucleotides of a yeast tRNA was found by Robert W. Holley in 1965, [ 78 ] winning Holley the 1968 Nobel Prize in Medicine (shared with Har Gobind ...

  5. Messenger RNA - Wikipedia

    en.wikipedia.org/wiki/Messenger_RNA

    5' cap structure. A 5' cap (also termed an RNA cap, an RNA 7-methylguanosine cap, or an RNA m 7 G cap) is a modified guanine nucleotide that has been added to the "front" or 5' end of a eukaryotic messenger RNA shortly after the start of transcription. The 5' cap consists of a terminal 7-methylguanosine residue that is linked through a 5'-5 ...

  6. Nucleic acid structure determination - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_structure...

    CryoEM of nucleic acid has been done on ribosomes, [7] viral RNA, [8] and single-stranded RNA structures within viruses. [ 9 ] [ 10 ] These studies have resolved structural features at different resolutions from the nucleobase level (2-3 angstroms) up to tertiary structure motifs (greater than a nanometer).

  7. ViennaRNA Package - Wikipedia

    en.wikipedia.org/wiki/ViennaRNA_Package

    The ViennaRNA Package is software, a set of standalone programs and libraries used for predicting and analysing RNA nucleic acid secondary structures. [1] The source code for the package is released as free and open-source software and compiled binaries are available for the operating systems Linux, macOS, and Windows.

  8. Molecular Structure of Nucleic Acids: A Structure for ...

    en.wikipedia.org/wiki/Molecular_Structure_of...

    In 1951, Pauling published the structure of the alpha helix, a fundamentally important structural component of proteins. In early 1953, Pauling published a triple helix model of DNA, which subsequently turned out to be incorrect. [3] Both Crick, and particularly Watson, thought that they were racing against Pauling to discover the structure of DNA.

  9. Tetraloop - Wikipedia

    en.wikipedia.org/wiki/Tetraloop

    Structure of a GNRA tetraloop from a group I self-splicing intron. [1] Tetraloops are a type of four-base hairpin loop motifs in RNA secondary structure that cap many double helices. [2] There are many variants of the tetraloop. The published ones include ANYA, [3] [4] CUYG, [5] GNRA, [6] UNAC [7] and UNCG. [8]