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  2. Follicular lymphoma - Wikipedia

    en.wikipedia.org/wiki/Follicular_lymphoma

    In situ follicular lymphoma is an accumulation of monoclonal B cells (i.e. cells descendent from a single ancestral cell) in the germinal centers of lymphoid tissue. These cells commonly bear a pathological genomic abnormality, i.e. a translocation between position 32 on the long (i.e. "q") arm of chromosome 14 and position 21 on chromosome 18's q arm.

  3. International Prognostic Index - Wikipedia

    en.wikipedia.org/wiki/International_Prognostic_Index

    Given the success of the IPI for intermediate grade lymphomas, an effort was undertaken to develop a similar prognostic index for the most common low-grade lymphoma, follicular lymphoma. The prognostic factors that emerged from this were: age, stage, number of lymph node areas involved, serum hemoglobin level, and serum LDH. [3]

  4. CRISPR Therapeutics Presents Data at the 2024 American ...

    lite.aol.com/tech/story/0022/20241209/9316263.htm

    Eligible disease subtypes include large B-cell lymphoma (LBCL), follicular lymphoma (FL) grade 1-3a, marginal zone lymphoma (MZL), and mantle cell lymphoma (MCL). CTX112 was infused after a standard course of lymphodepleting chemotherapy (3 days of 30 mg/m 2 fludarabine and 500 mg/m 2 cyclophosphamide).

  5. Pediatric-type follicular lymphoma - Wikipedia

    en.wikipedia.org/wiki/Pediatric-type_follicular...

    Pediatric-type follicular lymphoma (PTFL) is a disease in which malignant B-cells (i.e. a lymphocyte subtype originating from the bone marrow) accumulate in, overcrowd, and cause the expansion of the lymphoid follicles in, and thereby enlargement of the lymph nodes in the head and neck regions [1] and, less commonly, groin and armpit regions. [2]

  6. Small cleaved cells - Wikipedia

    en.wikipedia.org/wiki/Small_cleaved_cells

    When used to uniquely identify a type of lymphoma, they are usually categorized as follicular or diffuse . The "small cleaved cells" are usually centrocytes that express B-cell markers such as CD20. The disease is strongly correlated with the genetic translocation t(14;18), which results in juxtaposition of the bcl-2 proto-oncogene with the ...

  7. Duodenal-type follicular lymphoma - Wikipedia

    en.wikipedia.org/wiki/Duodenal-type_follicular...

    Duodenal-type follicular lymphoma (DFL) is a form of lymphoma in which certain lymphocyte types, the B-cell-derived centrocytes and centroblasts, form lymph node follicle-like structures principally in the duodenum and other parts of the small intestine.

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