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Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease in the United States, is a rare, terminal neurodegenerative disorder that results in the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction. [3] ALS is the most common form of the motor ...
ALSFRS-R includes 12 questions that can have a score of 0 to 4. A score of 0 on a question would indicate no function while a score of 4 would indicate full function. [4][5] This scale has been useful for doctors in diagnosing patients, measuring disease progression and also for researchers when selecting patients for a study and measuring the ...
TDP-43 is involved in the repair of DNA double-strand breaks. It is recruited to DNA damage sites and interacts with proteins involved in the repair process of non-homologous end joining. [9] FUS, which codes for "Fused in sarcoma" protein, is associated with 1–5% of familial ALS and less than 1% of sporadic ALS. FUS is an RNA-binding protein ...
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10 Gigabit Ethernet (abbreviated 10GE, 10GbE, or 10 GigE) is a group of computer networking technologies for transmitting Ethernet frames at a rate of 10 gigabits per second. It was first defined by the IEEE 802.3ae-2002 standard.
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Specialty. Neurology. Motor neuron diseases or motor neurone diseases (MNDs) are a group of rare neurodegenerative disorders that selectively affect motor neurons, the cells which control voluntary muscles of the body. [1][2] They include amyotrophic lateral sclerosis (ALS), [3][4] progressive bulbar palsy (PBP), pseudobulbar palsy, progressive ...