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Naloxone is useful in treating both acute opioid overdose and respiratory or mental depression due to opioids. [13] Whether it is useful in those in cardiac arrest due to an opioid overdose is unclear. [21] It is included as a part of emergency overdose response kits distributed to heroin and other opioid drug users, and to emergency responders.
Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. [3] It is used to treat opioid use disorder, and reduces the mortality of opioid use disorder by 50% (by reducing the risk of overdose on full-agonist opioids such as heroin or fentanyl).
The most common symptoms of overdose include central nervous system (CNS) depression, impaired balance, ataxia, and slurred speech. Severe symptoms include coma and respiratory depression. Supportive care is the mainstay of treatment of benzodiazepine overdose. There is an antidote, flumazenil, but its use is controversial. [2]
Like methadone, Suboxone blocks both the effects of heroin withdrawal and an addict’s craving and, if used properly, does it without causing intoxication. Unlike methadone, it can be prescribed by a certified family physician and taken at home, meaning a recovering addict can lead a normal life, without a daily early-morning commute to a clinic.
In an effort to make the drug available to more people, the Food and Drug Administration on Wednesday, March 29, approved Narcan, a nasal spray version of naloxone, to be sold over the counter ...
The state and L.A. County have worked hard to make Naloxone more widely available. One of the hurdles, though, has been the price of the inhalable version, Narcan. Naloxone helps prevent opioid ...
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