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This inhibits the synthesis of pro-inflammatory factors that induce asthma attacks and exacerbations, achieving anti-inflammatory effects. [19] For asthma maintenance therapy, methylxanthines are taken orally. [2] Therapeutic drug monitoring is required for patients on methylxanthines as the therapeutic range is narrow.
Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. [1] It is used to treat chronic obstructive pulmonary disease (COPD) and asthma. [2] Its pharmacology is similar to other methylxanthine drugs (e.g., theobromine and caffeine). [1]
Print/export Download as PDF; Printable version; In other projects ... (trade name Marax) is a drug that was used for the treatment of asthma.
Treatment for exercise-induced asthma is similar to other forms of the condition; the main difference is that you will take your medication before exercising as a preventive measure.
Print/export Download as PDF; Printable version; In other projects ... 8-Methoxymethyl-3-isobutyl-1-methylxanthine; Methylliberine; 7-Methylxanthine;
7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine). [ 1 ] [ 2 ] It is a non-selective antagonist of the adenosine receptors .
Because it has no effect on asthma symptoms when used alone, it is most often paired with a short-acting β 2-adrenergic agonist. While it is considered a relief or rescue medication, it can take a full hour to begin working. For this reason, it plays a secondary role in acute asthma treatment. Dry throat is the most common side effect.
IBMX (3-isobutyl-1-methylxanthine), like other methylxanthine derivatives, is both a: competitive non-selective phosphodiesterase inhibitor [1] which raises intracellular cAMP, activates PKA, inhibits TNFα [2] [3] and leukotriene [4] synthesis, and reduces inflammation and innate immunity, [4] and; nonselective adenosine receptor antagonist. [5]
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