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The first commercially sold sodium hyaluronate had been developed by Endre Alexander Balazs under the brand name of Healon, manufactured by Pharmacia AB in Sweden in 1980. In 1986, sodium hyaluronate was used as an intra-articular injection to treat osteoarthritis of the knee with the product Hyalart/Hyalgan by Fidia of Italy. [27]
Alkylation of imidazole (2) with bromoketone (1) prepared from o,p-dichloroacetophenone affords the displacement product (3). Reduction of the ketone with sodium borohydride gives the corresponding alcohol ( 4 ).
Savlon is a brand of antibacterial personal care products with the active ingredients of cetrimide and chlorhexidine gluconate. [1] Commonly sold as a cream , the product range also includes antiseptic sprays, sticking plasters and other antiseptic products.
Hyaluronic acid is a polymer of disaccharides, which are composed of D-glucuronic acid and N-acetyl-D-glucosamine, linked via alternating β-(1→4) and β-(1→3) glycosidic bonds. Hyaluronic acid can be 25,000 disaccharide repeats in length. Polymers of hyaluronic acid can range in size from 5,000 to 20,000,000 Da in vivo.
Calcium stearoyl-2-lactylate (calcium stearoyl lactylate or CSL) or E482 is a versatile, FDA approved food additive.It is one type of a commercially available lactylate.CSL is non-toxic, [3] [4] biodegradable, [5] and typically manufactured using biorenewable feedstocks.
Preparation H is an American brand of medications that is made by Pfizer, used in the treatment of hemorrhoids.Hemorrhoids are caused at least in part by inflamed blood vessels, and most versions of Preparation H work by reducing inflammation in blood vessels.
Diclofenac, sold under the brand name Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. [6] [9] It can be taken orally (swallowed by mouth), inserted rectally as a suppository, injected intramuscularly, injected intravenously, applied to the skin topically, or through eye drops.
Sodium laureth sulfate (SLES), an accepted contraction of sodium lauryl ether sulfate, also called sodium alkylethersulfate, is an anionic detergent and surfactant found in many personal care products (soaps, shampoos, toothpaste, etc.) and for industrial uses. SLES is an inexpensive and very effective foaming agent. [1]
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