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The lacuna are situated between the lamellae, and consist of a number of oblong spaces. In an ordinary microscopic section, viewed by transmitted light, they appear as fusiform opaque spots. Each lacuna is occupied during life by a branched cell, termed an osteocyte, bone-cell or bone-corpuscle.
Isogenous groups differentiate into individual chondrocytes where they continue to produce and deposit extracellular matrix (ECM), lengthening the cartilage and increasing its diameter.
The number of chondrocyte cells created and their maturation process can be influenced by multiple different genes and proteins. Two proteins, bone morphogenetic protein 4 (BMP-4) and fibroblast growth factor 2 (FGF2) have been seen to influence the amount of differentiation into chondrocytes. [ 4 ]
In embryogenesis, the skeletal system is derived from the mesoderm germ layer. Chondrification (also known as chondrogenesis) is the process by which cartilage is formed from condensed mesenchyme tissue, which differentiates into chondroblasts and begins secreting the molecules (aggrecan and collagen type II) that form the extracellular matrix.
In cases like this, the body will form a scar in the area using a special type of cartilage called fibrocartilage. [2] Fibrocartilage is a tough, dense, and fibrous material that helps fill in the torn part of the cartilage; however, it is not an ideal replacement for the smooth, glassy articular cartilage that normally covers the surface of ...
Bone canaliculi are microscopic canals between the lacunae of ossified bone.The radiating processes of the osteocytes (called filopodia) project into these canals. These cytoplasmic processes are joined together by gap junctions.
Also found among the Roman coins were 72 gold aurei, dated from 18 B.C. to 47 A.D. Those coins show no signs of wear and likely came from a pile of freshly minted coins, according to the Cultural ...
Arthroscopic image of a central triangular fibrocartilage complex (TFCC) tear. X-ray: X-rays of the wrist are made in two directions: posterior-anterior (PA) and lateral. Radiographs are useful to diagnose or rule out possible bone fractures, a positive ulnar variance or osteoarthritis. The TFCC is not visible on an X-ray, regardless of its ...