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Aureobasidium melanogenum, formerly known as Aureobasidium pullulans var. melanogenum is a ubiquitous black, yeast-like fungus that is found mainly in freshwater habitats. . The species also includes strains causing human infections, which were previously classified as A. pullulans
The exact biochemical processes in the suggested melanin-based synthesis of organic compounds or other metabolites for fungal growth, including the chemical intermediates (such as native electron donor and acceptor molecules) in the fungal cell and the location and chemical products of this process, are unknown.
Melanin (/ ˈ m ɛ l ə n ɪ n / ⓘ; from Ancient Greek μέλας (mélas) 'black, dark') is a family of biomolecules organized as oligomers or polymers, which among other functions provide the pigments of many organisms. [1] Melanin pigments are produced in a specialized group of cells known as melanocytes.
The term "phaeohyphomycosis" was introduced to determine infections caused by dematiaceous (pigmented) filamentous fungi which contain melanin in their cell walls. [11] Phaeohyphomycosis is an uncommon infection, but the number of cases reported has been increasing in recent years. Fungal melanin is thought to be a virulence factor.
Cladophialophora bantiana (C. bantiana) is a melanin producing mold known to cause brain abscesses in humans. [1] It is one of the most common causes of systemic phaeohyphomycosis in mammals. [2] Cladophialophora bantiana is a member of the ascomycota and has been isolated from soil samples from around the world. [3]
In 2014, the American research group was awarded a patent for a method of enhancing the growth of microorganisms through increasing melanin content. The inventors of this process claimed their fungi were employing radiosynthesis, and hypothesized that radiosynthesis may have played a role in early life on Earth, by allowing melanized fungi to ...
Presence of 1,8-dihydroxynaphthalene melanin in the cell wall [9] confers to the microfungi their characteristic olivaceous to dark brown/black colour. The consortium comprises two phylogenetically very different fungal groups. [10] [11] Many are found in the orders Capnodiales, Dothideales, and Pleosporales (class Dothideomycetes). These black ...
l-Dopaquinone also known as o-dopaquinone is a metabolite of L-DOPA (L-dihydroxyphenylalanine) and a precursor of melanin. [ 1 ] [ 2 ] Biosynthesis of melanin occurs in melanocytes , where tyrosine is converted into DOPA and then dopaquinone, which goes on to be formed into pheomelanin or eumelanin.