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2. Neurogenic claudication - Wikipedia

   en.wikipedia.org/wiki/Neurogenic_claudication

   Less commonly, the cause of spinal stenosis may be present at birth as seen in achondroplasia, spina bifida, and certain mucopolysaccharidoses. [15] In addition to spinal stenosis, other lower back conditions such as spondylosis, tumors, infections and herniated or ruptured discs can cause NC. These conditions contribute to the potential ...

3. Gabapentin - Wikipedia

   en.wikipedia.org/wiki/Gabapentin

   The oral bioavailability of gabapentin is approximately 80% at 100 mg administered three times daily once every 8 hours, but decreases to 60% at 300 mg, 47% at 400 mg, 34% at 800 mg, 33% at 1,200 mg, and 27% at 1,600 mg, all with the same dosing schedule.

4. Spinal stenosis - Wikipedia

   en.wikipedia.org/wiki/Spinal_stenosis

   Moderate to severe spinal stenosis at the levels of L3/4 and L4/5 [further explanation needed] The diagnosis of spinal stenosis involves a complete evaluation of the spine. The process usually begins with a medical history and physical examination. X-ray and MRI scans are typically used to determine the extent and location of the nerve compression.

5. Gabapentinoid - Wikipedia

   en.wikipedia.org/wiki/Gabapentinoid

   The oral bioavailability of gabapentin enacarbil (as gabapentin) is greater than or equal to 68%, across all doses assessed (up to 2,800 mg), with a mean of approximately 75%. [ 25 ] [ 1 ] In contrast to the other gabapentinoids, the pharmacokinetics of phenibut have been little-studied, and its oral bioavailability is unknown. [ 28 ]

6. Lumbar spinal stenosis - Wikipedia

   en.wikipedia.org/wiki/Lumbar_spinal_stenosis

   Lumbar spinal stenosis (LSS) is a medical condition in which the spinal canal narrows and compresses the nerves and blood vessels at the level of the lumbar vertebrae. Spinal stenosis may also affect the cervical or thoracic region, in which case it is known as cervical spinal stenosis or thoracic spinal stenosis. Lumbar spinal stenosis can ...

7. Spinal disease - Wikipedia

   en.wikipedia.org/wiki/Spinal_disease

   Lumbar spinal stenosis is very prevalent with 9.3% of the general population producing symptoms and the number is continuing to rise in patients older than 60. [16] It's generally an indication for spinal surgery in patients older than 65 years of age. [17]