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[122] [126] High doses or levels of AAS, including testosterone, can cause polycythemia—high red blood cell and/or hemoglobin levels that increase the risk of stroke—as an adverse effect. [ 121 ] [ 122 ] Conversely, whether via castration, NSAA monotherapy, or CAB , decreased erythropoiesis resulting in mild anemia is a common side effect ...
Testosterone can be taken by a variety of different routes of administration. [2] [3] These include oral, buccal, sublingual, intranasal, transdermal (gels, creams, patches, solutions), vaginal (creams, gels, suppositories), rectal (suppositories), by intramuscular or subcutaneous injection (in oil solutions or aqueous suspensions), and as a subcutaneous implant.
This is particularly so considering that bicalutamide increases circulating testosterone levels, and by extension gonadal testosterone production, by up to two-fold in males, [88] and that only a small fraction of normal intratesticular testosterone levels, and by extension androgen action, appears to be necessary to maintain spermatogenesis.
Testosterone replacement therapy works by increasing the amount of testosterone in your system. You’ll take synthetic testosterone to make up for low levels of the natural hormone in your body.
[23] [24] [25] However, when given to men with hypogonadism in the short- and medium-term, testosterone replacement therapy does not increase the risk of cardiovascular events (including strokes and heart attacks and other heart diseases). [2] The long-term safety of the therapy is not known yet. [26] [27]
The male hormone, testosterone, is produced in limited quantities following treatment with Zeuterin, but after two years, testosterone production is similar to that in untreated dogs. [1] The continuing presence of testosterone means that, unlike surgical castration, chemical castration does not remove the risk of testosterone-associated ...
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Mayo Clinic is a nonprofit hospital system with campuses in Rochester, Minnesota; Scottsdale and Phoenix, Arizona; and Jacksonville, Florida. [22] [23] Mayo Clinic employs 76,000 people, including more than 7,300 physicians and clinical residents and over 66,000 allied health staff, as of 2022. [5]