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Folate deficiency, also known as vitamin B 9 deficiency, is a low level of folate and derivatives in the body. [1] This may result in megaloblastic anemia in which red blood cells become abnormally large, and folate deficiency anemia is the term given for this medical condition. [3] Signs of folate deficiency are often subtle. [4]
Folate deficiency is diagnosed by analyzing a complete blood count (CBC) and plasma vitamin B 12 and folate levels. A serum folate of 3 μg/L or lower indicates deficiency. [98] Serum folate level reflects folate status, but erythrocyte folate level better reflects tissue stores after intake.
Deficiency can also result from rare genetic factors, such as mutations in the MTHFR gene that lead to compromised folate metabolism. [33] [34] Cerebral folate deficiency is a rare condition in which concentrations of folate are low in the brain despite being normal in the blood. [35] Vitamin B 12 deficiency: Anemia, neurological and digestive ...
Eating whole foods is a common recommendation for combatting everyday fatigue, with leafy greens, nuts, seeds, and lean proteins all contributing to a well-rounded diet that should make a ...
A new study challenges traditional beliefs about folate after finding that reducing vitamin B9 intake can promote healthier metabolisms in aging mice. ... Their folate levels were 30-40% of those ...
[56] [57] Low levels of serum vitamin B 12 may be caused by other factors than B 12 deficiency, such as folate deficiency, pregnancy, oral contraceptive use, haptocorrin deficiency, and myeloma. [57] High serum levels may caused by supplementing with vitamin B 12, present of antibodies to intrinsic factor, or due to underlying condition. [56]
A 1978 study examined the effect of sunlight on folate—a vitamin B complex—levels. [citation needed] The study found that even short periods of intense sunlight are able to halve folate levels if someone has light skin. Low folate levels are correlated with neural tube defects, such as anencephaly and spina bifida.
Still, your ob-gyn may choose to do a hormone test to see if your follicle-stimulating hormone levels are elevated or to check thyroid function. When it comes to a diagnosis, it all comes back to ...