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7-Hydroxycannabidiol (7-OH-CBD) is an active metabolite of cannabidiol, generated in the body from cannabidiol by the action of the enzyme CYP2C19. [1] While methods have been developed for its synthetic production, [2] and measurement of levels in the body following consumption of cannabidiol, [3] its pharmacology has been relatively little studied, though it has been found to possess similar ...
CBD is hydroxylated by P450 liver enzymes into 7-OH-CBD. Its metabolites are products of primarily CYP2C19 and CYP3A4 activity, with potential activity of CYP1A1, CYP1A2, CYP2C9, and CYP2D6. [69] Similar to delta-9-THC, a majority of CBD is excreted in feces and some in the urine. [57] The terminal half-life is approximately 18–32 hours. [70]
[23] [24] It may be supplied as CBD oil containing only CBD as the active ingredient (excluding THC or terpenes), CBD-dominant hemp extract oil, capsules, dried cannabis, or prescription liquid solution. [4] [20] CBD does not have the same psychoactivity as THC, [25] [26] and can modulate the psychoactive effects of THC on the body if both are ...
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Cancer symptoms and medication side effects: CBD is not a treatment for cancer. However, it can be used as a supplemental treatment to help ease pain and other symptoms associated with cancer ...
Such effects may include analgesia, decreased inflammation, decreased spasticity, and anti-seizure effects. [26] Cannabis edibles with CBD can decrease symptoms of psychosis and anxiety. [25] Edible oils, tinctures, pills, and gummies have been prescribed to people with cancer to potentially improve poor appetite, pain, or weight loss. [27]
Unlike CBD oil and CBD tincture, CBD capsules offer a standard dose of cannabidiol without the hassle of calculating or measuring. “There’s a lot of control over the product and it’s easy ...