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Testosterone secretion by the interstitial cells of the testes then causes the growth and development of the mesonephric ducts into male secondary sex organs. [7] The Müllerian ducts atrophy, but traces of their anterior ends are represented by the appendices testis ( hydatids of Morgagni of the male), while their terminal fused portions form ...
Thus, spermatogenesis is the male version of gametogenesis, of which the female equivalent is oogenesis. In mammals it occurs in the seminiferous tubules of the male testes in a stepwise fashion. Spermatogenesis is highly dependent upon optimal conditions for the process to occur correctly, and is essential for sexual reproduction.
Because its main function is to nourish developing sperm cells through the stages of spermatogenesis, the Sertoli cell has also been called the "mother" or "nurse" cell. [10] Sertoli cells also act as phagocytes, consuming the residual cytoplasm during spermatogenesis. Translocation of cells from the basal lamina to the lumen of the ...
Spermatogenesis, the process for producing spermatozoa, takes place in the seminiferous tubules. During spermatogenesis, the DNA of spermatogenic cells in the seminiferous tubules is subject to damage from such sources as reactive oxygen species. [1] The genomic integrity of spermatogenic cells is protected by DNA repair processes. [2]
Spermatogonia going through mitosis to form primary spermatocytes in Grasshopper testes. Spermatocytogenesis. At puberty, spermatogonia located along the walls of the seminiferous tubules within the testis will be initiated and start to divide mitotically, forming two types of A cells that contain an oval shaped nucleus with a nucleolus attached to the nuclear envelope; one is dark (Ad) and ...
Spermiogenesis is the final stage of spermatogenesis, during which the spermatids develop into mature spermatozoa. At the beginning of the stage, the spermatid is a more or less circular cell containing a nucleus , Golgi apparatus , centriole and mitochondria ; by the end of the process, it has radically transformed into an elongated ...
These cells do not directly participate in producing sperm, instead serving to maintain the supply of stem cells for spermatogenesis. Each type Ad spermatogonium divides to produce another type Ad spermatogonium, which can further carry on spermatogenesis, and one type Ap spermatogonium , which differentiates further.
CYP17A1 has both 17α-hydroxylase activity (EC 1.14.14.19) and 17,20-lyase activity (EC 1.14.14.32). The 17α-hydroxylase activity of CYP17A1 is required for the generation of glucocorticoids such as cortisol, but both the hydroxylase and 17,20-lyase activities of CYP17A1 are required for the production of androgenic and oestrogenic sex ...