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The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
Cutis, often termed the "true skin", is composed of the epidermis and the dermis. [1] The dermis contains blood vessels, sweat glands, sebaceous glands, and hair follicles. [2] The epidermis and the dermis contain sensory nerve endings to detect changes in the environment. [2] The cutis is the layer located above the subcutis. [2
The blood vessels in the dermis provide nourishment and waste removal from its own cells as well as from the stratum basale of the epidermis. The dermis is structurally divided into two areas: a superficial area adjacent to the epidermis, called the papillary region , and a deep thicker area known as the reticular region .
Blood vessels transport blood cells, nutrients, and oxygen to most of the tissues of a body. They also take waste and carbon dioxide away from the tissues. [2] Some tissues such as cartilage, epithelium, and the lens and cornea of the eye are not supplied with blood vessels and are termed avascular.
The reticular layer is the deep layer of the dermis and consists of the dense irregular connective tissue. These layers serve to give elasticity to the integument, allowing stretching and conferring flexibility, while also resisting distortions, wrinkling, and sagging. [3] The dermal layer provides a site for the endings of blood vessels and ...
A glomus body (or glomus organ; plural glomera) is a component of the dermis layer of the skin, involved in body temperature regulation. [1] [2] The glomus body is a small arteriovenous anastomosis surrounded by a capsule of connective tissue. Glomera are most numerous in the fingers and toes.
The endothelium is a thin layer of single flat cells that line the interior surface of blood vessels and lymphatic vessels. [1] Endothelium is of mesodermal origin. Both blood and lymphatic capillaries are composed of a single layer of endothelial cells called a monolayer. In straight sections of a blood vessel, vascular endothelial cells ...
The dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. The dermis provides tensile strength and elasticity to the skin through an extracellular matrix composed of collagen fibrils , microfibrils , and elastic fibers , embedded in hyaluronan and proteoglycans . [ 15 ]