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  2. Isopropyl β-D-1-thiogalactopyranoside - Wikipedia

    en.wikipedia.org/wiki/Isopropyl_β-D-1...

    Isopropyl β-d-1-thiogalactopyranoside (IPTG) is a molecular biology reagent. This compound is a molecular mimic of allolactose , a lactose metabolite that triggers transcription of the lac operon , and it is therefore used to induce protein expression where the gene is under the control of the lac operator .

  3. T7 expression system - Wikipedia

    en.wikipedia.org/wiki/T7_expression_system

    IPTG is a reagent which mimics the structure of allolactose, and can therefore bind to the lac repressor and prevent it from inhibiting gene expression. Once enough IPTG is added, the T7 gene is normally transcribed and so transcription of the gene of interest downstream of the T7 promoter also begins. [6]

  4. β-Galactosidase - Wikipedia

    en.wikipedia.org/wiki/Β-Galactosidase

    Its production may be induced by a non-hydrolyzable analog of allolactose, IPTG, which binds and releases the lac repressor from the lac operator, thereby allowing the initiation of transcription to proceed. It is commonly used in molecular biology as a reporter marker to monitor gene expression.

  5. Maternal physiological changes in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Maternal_physiological...

    Women are 4-5 times more likely to develop a clot during pregnancy and in the postpartum period than when they are not pregnant. [25] Hypercoagulability in pregnancy likely evolved to protect women from hemorrhage at the time of miscarriage or childbirth. In developing countries, the leading cause of maternal death is still hemorrhage. [25]

  6. Synthetic biological circuit - Wikipedia

    en.wikipedia.org/wiki/Synthetic_biological_circuit

    IPTG, a molecule similar to lactose, but with a sulfur bond that is not hydrolyzable so that E. coli does not digest it, is used to activate or "induce" the production of the new protein. Once the cells are induced, it is difficult to remove IPTG from the cells and therefore it is difficult to stop expression.

  7. 'Bleeding Eye' Virus Sparks Travel Warning and Worldwide ...

    www.aol.com/bleeding-eye-virus-sparks-travel...

    A warning has been issued to travelers over the spread of three diseases, including the Marburg virus. It’s a close cousin of Ebola that’s been dubbed the “bleeding eye” virus due to one ...

  8. Donald Trump once threatened to jail Mark Zuckerberg, but ...

    www.aol.com/finance/donald-trump-once-threatened...

    Donald Trump was threatening to send Meta CEO Mark Zuckerberg to prison “for life” if he interfered in the election just a few short months ago—but come Thanksgiving, the bad blood appears ...

  9. Immune tolerance in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Immune_tolerance_in_pregnancy

    Immune tolerance in pregnancy or maternal immune tolerance is the immune tolerance shown towards the fetus and placenta during pregnancy. This tolerance counters the immune response that would normally result in the rejection of something foreign in the body, as can happen in cases of spontaneous abortion .

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