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The opioid epidemic took hold in the U.S. in the 1990s. Percocet, OxyContin and Opana became commonplace wherever chronic pain met a chronic lack of access to quality health care, especially in Appalachia. The Centers for Disease Control and Prevention calls the prescription opioid epidemic the worst of its kind in U.S. history.
Long-term opioid use can cause opioid-induced hyperalgesia, which is a condition in which the patient has increased sensitivity to pain. [101] All of the opioids can cause side effects. [70] Common adverse reactions in patients taking opioids for pain relief include nausea and vomiting, drowsiness, itching, dry mouth, dizziness, and constipation.
A 2021 review found little effect of using non-inhaled cannabis to relieve chronic pain. [8] According to a 2019 systematic review, there have been inconsistent results of using cannabis for neuropathic pain, spasms associated with multiple sclerosis and pain from rheumatic disorders, but
An opiate, in classical pharmacology, is a substance derived from opium. In more modern usage, the term opioid is used to designate all substances, both natural and synthetic, that bind to opioid receptors in the brain (including antagonists). Opiates are alkaloid compounds naturally found in the Papaver somniferum plant (opium poppy).
Delta-9-tetrahydrocannabinol, or THC, is the part of the cannabis plant that produces a “high” — a key reason marijuana helps with nausea and pain, he added.
However, studies have shown that non-opioid treatments for acute pain can be just as if not more effective than opioids at treating some acute pain conditions, which could be where VX-548 comes in.
The medical use of marijuana for pain relief could be safer than traditional opioids used for pain relief as marijuana cannot be overdosed on and is less addictive. Marijuana could also replace the use of common non-steroidal anti-inflammatory drugs (NSAIDs) such as Advil or Aleve that have been known to cause kidney or ulcer problems. [100]
Millions like me who suffer chronic pain need North Carolina to pass a medical marijuana bill. It would help us and the state. | Opinion Medical marijuana: I don’t want to rely on opioids for my ...