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Palpable hard lump, if the stone is located near the end of the duct. [1] [3] If the stone is near the submandibular duct orifice, the lump may be felt under the tongue. Lack of saliva coming from the duct (total obstruction). [3] Erythema (redness) of the floor of the mouth (infection). [3] Pus discharging from the duct (infection). [3]
The salivary glands in many vertebrates including mammals are exocrine glands that produce saliva through a system of ducts. Humans have three paired major salivary glands (parotid, submandibular, and sublingual), as well as hundreds of minor salivary glands. [1] Salivary glands can be classified as serous, mucous, or seromucous (mixed).
The third pair are the sublingual glands located underneath the tongue and their secretion is mainly mucous with a small percentage of saliva. Within the oral mucosa, and also on the tongue, palates, and floor of the mouth, are the minor salivary glands; their secretions are mainly mucous and they are innervated by the facial nerve . [12]
The paired submandibular glands (historically known as submaxillary glands) are major salivary glands located beneath the floor of the mouth.In adult humans, they each weigh about 15 grams and contribute some 60–67% of unstimulated saliva secretion; on stimulation their contribution decreases in proportion as parotid gland secretion rises to 50%. [1]
The submandibular duct may be affected by stones, known as sialolithiasis. [4] These may grow large, requiring surgery to remove. [4] Simple palpation may be used to identify the location of any stones before surgery. [4]
Sarcoidosis is a chronic systemic disease characterised by the production of non-caseating granulomas of unknown aetiology. It can affect any organ of the body, depressing cellular immunity and enhancing humoral immunity. Salivary gland involvement primarily involves both parotid glands, causing enlargement and swelling.
Merocrine – the cells of the gland excrete their substances by exocytosis into a duct; for example, pancreatic acinar cells, eccrine sweat glands [dubious – discuss], salivary glands, goblet cells, intestinal glands, tear glands, etc. Apocrine – the apical portion of the cytoplasm in the cell membrane, which contains the excretion, buds off.
Superficial anatomy or surface anatomy is important in human anatomy being the study of anatomical landmarks that can be readily identified from the contours or other reference points on the surface of the body. [1] With knowledge of superficial anatomy, physicians gauge the position and anatomy of deeper structures.