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It is the primary form of thyroid hormone found in the blood and acts as a prohormone of the more active thyroid hormone, triiodothyronine (T 3). [1] Thyroxine and its active metabolites are essential for regulating metabolic rate , supporting heart and muscle function , promoting brain development , and maintaining bone health .
Desiccated Thyroid became a commercial treatment option in 1934 with Westhroid, [citation needed]. In the early 1960s, desiccated thyroid hormones (thyroid extract) began to be replaced by levothyroxine (synthetic T4), or by combinations of T4 and T3. Replacement occurred faster in the United Kingdom than in North America, but by the 1980s more ...
Thyroid hormones act on nearly every cell in the body. They act to increase the basal metabolic rate, affect protein synthesis, help regulate long bone growth (synergy with growth hormone) and neural maturation, and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness. [12]
Thyroid disease in women is an autoimmune disease that affects the thyroid in women. This condition can have a profound effect during pregnancy and on the child. It also is called Hashimoto's thyroiditis (theye-royd-EYET-uhss). During pregnancy, the infant may be seriously affected and have a variety of birth defects.
[3] [5] [10] Even moderate weight loss can lower T3. [2] This may be primarily via reduced levels of leptin (the satisfaction hormone). Low leptin levels can downregulate hypothalamic TRH neurons and cause a reduction in TSH. [5] [10] Ιn fasting animals, administering leptin reverses NTIS symptoms and restores thyroid hormone concentrations. [5]
The company claims to have helped more than four million people lose weight and it’s tagline is “Go Lose Weight, Go Look Great, Go Love Life.” It all adds up to the “GOLO” diet, created ...
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