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The condition is commonly associated with vascular and cardiac changes associated with aging but can be caused by many other conditions, including congestive heart failure, kidney failure, liver cirrhosis, portal hypertension, trauma, alcoholism, altitude sickness, pregnancy, hypertension, sickle cell anemia, a compromised lymphatic system or merely long periods of time sitting or standing ...
Amlodipine works partly by vasodilation (relaxing the arteries and increasing their diameter). [10] It is a long-acting calcium channel blocker of the dihydropyridine type. [10] Amlodipine was patented in 1982, and approved for medical use in 1990. [12] It is on the World Health Organization's List of Essential Medicines. [13]
Certain drugs (for example, amlodipine) can cause pedal edema. Cerebral edema is extracellular fluid accumulation in the brain. [1] It can occur in toxic or abnormal metabolic states and conditions such as systemic lupus or reduced oxygen at high altitudes. It causes drowsiness or loss of consciousness, leading to brain herniation and death.
When symptoms grow worse (more on this later), heart failure can cause swelling in the ankles and legs, as well as swollen feet. This is due to edema, which is a fluid accumulation in the body ...
Leg pain or swelling can come with age or specific types of medical maladies — but the most common type of pain comes from general fatigue. If you’ve been on your feet all day or haven’t had ...
Amlodipine/benazepril, sold under the brand name Lotrel among others, is a fixed-dose combination medication used to treat high blood pressure. [1] It is a combination of amlodipine , as the besilate, a calcium channel blocker , and benazepril , an angiotensin converting enzyme inhibitor . [ 1 ]
Swelling: Some individuals may experience slight swelling (edema) in the lower legs alongside the rash. This swelling is typically mild and localized to the affected areas. [3] [2] Burning sensation: A burning or stinging sensation in the affected skin is commonly reported. This discomfort can range from mild to moderate in intensity. [3] [6]
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