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  2. Nicotine - Wikipedia

    en.wikipedia.org/wiki/Nicotine

    Urinary metabolites of nicotine, quantified as average percentage of total urinary nicotine [146] As nicotine enters the body, it is distributed quickly through the bloodstream and crosses the blood–brain barrier reaching the brain within 10–20 seconds after inhalation. [147] The elimination half-life of nicotine in the body is around two ...

  3. Effects of nicotine on human brain development - Wikipedia

    en.wikipedia.org/wiki/Effects_of_nicotine_on...

    The ability to quitting smoking is affected by genetic factors, including genetically based differences in the way nicotine is metabolized. [48] In the CYP450 system there are 173 genetic variants, which impacts how quickly nicotine is metabolizes by each individual. [49] The speed of metabolism impacts the regularity and quantity of nicotine ...

  4. Nicotinic acetylcholine receptor - Wikipedia

    en.wikipedia.org/wiki/Nicotinic_acetylcholine...

    Major subtype involved in some of the cognitive effects of nicotine. [55] Moreover, activation of (α 7) 5 could improve neurovascular coupling response in neurodegenerative disease [56] and neurogenesis in ischemic stroke. [57] Also involved in the pro-angiogenic effects of nicotine and accelerate the progression of chronic kidney disease in ...

  5. Cotinine - Wikipedia

    en.wikipedia.org/wiki/Cotinine

    Cotinine has an in vivo half-life of approximately 20 hours, and is typically detectable for several days (up to one week) after the use of tobacco. The level of cotinine in the blood, saliva, and urine is proportionate to the amount of exposure to tobacco smoke, so it is a valuable indicator of tobacco smoke exposure, including secondary (passive) smoke. [14]

  6. Microdosing nicotine: Could it actually be good for your ...

    www.aol.com/lifestyle/microdosing-nicotine-could...

    Nicotine may be safer than nicotine plus the other chemicals found in cigarettes and vapes, but on its own, nicotine has been associated with detrimental health effects as well, says Bhatnagar.

  7. Nicotinamide adenine dinucleotide - Wikipedia

    en.wikipedia.org/wiki/Nicotinamide_adenine_di...

    In cellular metabolism, NAD is involved in redox reactions, carrying electrons from one reaction to another, so it is found in two forms: NAD + is an oxidizing agent, accepting electrons from other molecules and becoming reduced; with H +, this reaction forms NADH, which can be used as a reducing agent to donate electrons.

  8. The Truth About Those Nicotine Pouches You’re ... - AOL

    www.aol.com/truth-those-nicotine-pouches...

    Nicotine pouches are small pouches that contain a mix of nicotine, flavors, and other chemicals, but they don’t contain tobacco leaf, says Brittney Keller-Hamilton, PhD, a researcher with the ...

  9. Cigarette smoking for weight loss - Wikipedia

    en.wikipedia.org/wiki/Cigarette_Smoking_for...

    Nicotine can also lower insulin levels in a person's bloodstream, which can reduce cravings for sugary foods. [4]: 418 Furthermore, “nicotine-triggered effects of adrenaline on the stomach’s musculature” lead to temporary feelings of subsided hunger. [4]

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