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The reinforcing effects of alcohol consumption are mediated by acetaldehyde generated by catalase and other oxidizing enzymes such as cytochrome P-4502E1 in the brain. [60] Although acetaldehyde has been associated with some of the adverse and toxic effects of ethanol, it appears to play a central role in the activation of the mesolimbic ...
The safety profile of fexofenadine is quite favorable, as no cardiovascular or sedative effects have been shown to occur even when taking 10 times the recommended dose. [25] Research on humans ranges from a single 800-mg dose, to a twice-daily, 690-mg dose for a month, with no clinically significant adverse effects, when compared to a placebo.
Since alcohol is absorbed into body water content, and men have more water in their bodies than women, for women there will be a higher blood alcohol concentration from the same amount of alcohol consumption. [22] Women are also thought to have less alcohol dehydrogenase (ADH) enzyme which is required to break down alcohol. [8]
Alcohol can increase your risk of cancer, but it can also prevent some heart attacks. Here's the complicated truth. What alcohol does to your brain and body, according to the latest science
Paraldehyde combined with chloral hydrate showed superiority over chlordiazepoxide with regard to life-threatening side effects and carbamazepine may have advantages for certain symptoms. [42] Long term anticonvulsant medications are not usually recommended in those who have had prior seizures due to withdrawal. [43]
Risk factors for developing alcohol dependence or misuse include drinking before the age of 15, genetics or a family history of alcohol problems and mental health conditions or a history of trauma ...
Alcohol tolerance is increased by regular drinking. [1] This reduced sensitivity to the physical effects of alcohol consumption requires that higher quantities of alcohol be consumed in order to achieve the same effects as before tolerance was established. Alcohol tolerance may lead to (or be a sign of) alcohol dependence. [1]
Short-term effects of alcohol consumption include intoxication and dehydration. Long-term effects of alcohol include changes in the metabolism of the liver and brain, with increased risk of several types of cancer and alcohol use disorder. [1] Alcohol intoxication affects the brain, causing slurred speech, clumsiness, and delayed reflexes.
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