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No screening test is wholly specific, and a high level of tumor marker can still be found in benign tumors. The only tumor marker currently used in screening is PSA (prostate-specific antigen). Diagnostics; Tumor markers alone can't be used for diagnostic purposes, due to lack of sensitivity and specificity. [5]
CA 15-3, for Carcinoma Antigen 15-3, is a tumor marker for many types of cancer, most notably breast cancer. [1] [2] [3]It is derived from MUC1. [4] CA 15-3 and associated CA 27-29 are different epitopes on the same protein antigen product of the breast cancer-associated MUC1 gene.
The Oncotype DX® breast cancer assay is one such test used to predict the likelihood of breast cancer recurrence. This test is intended for women with early-stage (Stage I or II), node-negative, estrogen receptor-positive (ER+) invasive breast cancer who will be treated with hormone therapy.
The Trial Early Serum Test Breast cancer (TESTBREAST) study includes 1,174 women in the Netherlands who are at a high risk of breast cancer, due to their family history or because they carry gene ...
CA 27.29 is a tumor marker for breast cancer. [1] It is a form of glycoprotein MUC1. [2] References This page was last edited on 4 November 2023 ...
Consequently, CEA is usually present at very low levels in the blood of healthy adults (about 2–4 ng/mL). [2] However, the serum levels are raised in some types of cancer, which means that it can be used as a tumor marker in clinical tests. Serum levels can also be elevated in heavy smokers. [3]
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