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  2. Management of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Management_of_schizophrenia

    [149] [150] Clozapine is of benefit to around half of this group although it has the potentially serious side effect of agranulocytosis (lowered white blood cell count) in less than 4% of people. [151] [152] [153] Between 12 and 20 per cent will not respond to clozapine and this group is said to have ultra treatment resistant schizophrenia.

  3. Clozapine - Wikipedia

    en.wikipedia.org/wiki/Clozapine

    Clozapine, sold under the brand name Clozaril among others, is a psychiatric medication and was the first atypical antipsychotic to be discovered. [7] It is used primarily to treat people with schizophrenia and schizoaffective disorder who have had an inadequate response to two other antipsychotics, or who have been unable to tolerate other drugs due to extrapyramidal side effects.

  4. List of psychotropic medications - Wikipedia

    en.wikipedia.org/wiki/List_of_psychotropic...

    Saphris – atypical antipsychotic used to treat schizophrenia and bipolar disorder; Serax – anti-anxiety medication of the benzodiazepine class, often used to help during detoxification from alcohol or other addictive substances; Serentil (mesoridazine) – an antipsychotic drug used in the treatment of schizophrenia [1]

  5. Herbert Y. Meltzer - Wikipedia

    en.wikipedia.org/wiki/Herbert_Y._Meltzer

    Herbert Y. Meltzer is an American scientist and professor of psychiatry and behavioral sciences, pharmacology and physiology and director of the Translational Neuropharmacology Program at Northwestern University, best known for his research on the treatment of schizophrenia. [1] He is the author of over 1,000 publications. [2]

  6. Antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Antipsychotic

    Used for the treatment of schizophrenia and acute mania associated with bipolar disorder. Clozapine (Clozaril) – Of the dibenzodiazepine class of atypical antipsychotics. Requires routine laboratory monitoring of complete blood counts every one to four weeks due to the risk of agranulocytosis. It has unparalleled efficacy in the treatment of ...

  7. Typical antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Typical_antipsychotic

    Typical antipsychotics (also known as major tranquilizers, and first generation antipsychotics) are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia). Typical antipsychotics may also be used for the treatment of acute mania, agitation, and other conditions.

  8. Dopamine antagonist - Wikipedia

    en.wikipedia.org/wiki/Dopamine_antagonist

    Dopamine receptor flow chart. Dopamine receptors are all G protein–coupled receptors, and are divided into two classes based on which G-protein they are coupled to. [1] The D 1-like class of dopamine receptors is coupled to Gα s/olf and stimulates adenylate cyclase production, whereas the D 2-like class is coupled to Gα i/o and thus inhibits adenylate cyclase production.

  9. Atypical antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Atypical_antipsychotic

    Clozapine is considered a first choice treatment for treatment resistant schizophrenia, especially in the short term; in the longer-terms the risks of adverse effects complicate the choice. [19] In turn, risperidone, olanzapine, and aripiprazole have been recommended for the treatment of first-episode psychosis. [20] [21]

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